2024
Assessment of immune cells in the uterine fluid at the time of the embryo transfer
Strbo N, Rodriguez S, Padula L, Fisher E, Lyons A, Rodriguez C, Rivas K, Ibrahim M, Paidas M, Attia G. Assessment of immune cells in the uterine fluid at the time of the embryo transfer. American Journal Of Reproductive Immunology 2024, 91: e13842. PMID: 38650366, DOI: 10.1111/aji.13842.Peer-Reviewed Original ResearchMeSH KeywordsAdultBody FluidsEmbryo ImplantationEmbryo TransferEndometriumFemaleFertilization in VitroHumansPregnancyProspective StudiesUterusConceptsGamma delta T cellsFrozen embryo transferLower uterusAssisted reproductive technologyIn vitro fertilizationTransfer catheterT cellsEmbryo transferTime of implantationImmune milieuUpper uterusImmune cellsUltrasound guidanceExpression of CD4+ T cellsAssessment of immune cellsImprove IVF outcomesCD8+ T cellsCD4+ T cellsPopulation of T cellsComposition of immune cellsLower uterine segmentTime of embryo transferExpression of CD3+T regulatory cellsCD3+ cells
2013
Exploring the Role of Antithrombin Replacement for the Treatment of Preeclampsia: A Prospective Randomized Evaluation of the Safety and Efficacy of Recombinant Antithrombin in Very Preterm Preeclampsia (PRESERVE‐1)
Paidas MJ, Sibai BM, Triche EW, Frieling J, Lowry S, Group T. Exploring the Role of Antithrombin Replacement for the Treatment of Preeclampsia: A Prospective Randomized Evaluation of the Safety and Efficacy of Recombinant Antithrombin in Very Preterm Preeclampsia (PRESERVE‐1). American Journal Of Reproductive Immunology 2013, 69: 539-544. PMID: 23444920, DOI: 10.1111/aji.12091.Peer-Reviewed Original ResearchConceptsProspective Randomized EvaluationAntithrombin replacementWeeks' gestationRandomized EvaluationRecombinant antithrombinTreatment of preeclampsiaRecombinant human ATExpectant managementPreterm preeclampsiaPrimary endpointMaternal indicationsGestational ageStudy enrollmentAT therapyPreeclampsia studyPreeclampsiaGestationHuman ATAT replacementPharmacokinetic activityAntithrombinEfficacySafetyLaboratory assaysDelivery
2005
Protein Z, protein S levels are lower in patients with thrombophilia and subsequent pregnancy complications
PAIDAS MJ, KU D, LEE M, MANISH S, THURSTON A, LOCKWOOD CJ, ARKEL YS. Protein Z, protein S levels are lower in patients with thrombophilia and subsequent pregnancy complications. Journal Of Thrombosis And Haemostasis 2005, 3: 497-501. PMID: 15748239, DOI: 10.1111/j.1538-7836.2005.01158.x.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesNormal pregnancy outcomeProtein S levelsPZ levelsPregnancy outcomesProtein SSubsequent pregnancy complicationsProtein ZAdditional risk factorsFree PS antigenPregnancy complicationsPregnant controlsThird trimesterPlasma levelsRisk factorsPatientsThrombophiliaPS antigenS levelsWomenSignificant decreasePS levelsOutcomesLow levelsTrimester
2000
Change in Cervical Length After Cerclage as a Predictor of Preterm Delivery
DIJKSTRA K, FUNAI E, O'NEILL L, REBARBER A, PAIDAS M, YOUNG B. Change in Cervical Length After Cerclage as a Predictor of Preterm Delivery. Obstetrics And Gynecology 2000, 96: 346-350. DOI: 10.1097/00006250-200009000-00006.Peer-Reviewed Original ResearchConceptsCervical lengthProphylactic cerclagePregnancy outcomesWeeks' gestationSerial cervical length measurementsMean cervical lengthMethods Eighty womenTransvaginal ultrasonographic evaluationCervical length measurementEarly third trimesterTransvaginal ultrasound examinationCerclage groupPreterm deliveryPreterm birthSerial followTerm deliveryPrimary physicianThird trimesterUltrasonographic evaluationUltrasound examinationCerclageMost womenPatientsGestationSignificant associationChange in cervical length after cerclage as a predictor of preterm delivery.
Dijkstra K, Funai E, O'Neill L, Rebarber A, Paidas M, Young B. Change in cervical length after cerclage as a predictor of preterm delivery. Obstetrics And Gynecology 2000, 96: 346-50. PMID: 10960624, DOI: 10.1016/s0029-7844(00)00924-8.Peer-Reviewed Original ResearchConceptsCervical lengthProphylactic cerclagePregnancy outcomesWeeks' gestationSerial cervical length measurementsMean cervical lengthTransvaginal ultrasonographic evaluationCervical length measurementEarly third trimesterTransvaginal ultrasound examinationCerclage groupPreterm deliveryPreterm birthSerial followTerm deliveryPrimary physicianThird trimesterUltrasonographic evaluationUltrasound examinationCerclageMost womenPatientsGestationSignificant associationLogistic regression
1999
Change in Cervical Length After Prophylactic Cerclage
FUNAI E, PAIDAS M, REBARBER A, O'NEILL L, ROSEN T, YOUNG B. Change in Cervical Length After Prophylactic Cerclage. Obstetrics And Gynecology 1999, 94: 117-119. DOI: 10.1097/00006250-199907000-00023.Peer-Reviewed Original ResearchMeSH KeywordsAdultCervix UteriFemaleHumansPregnancyProspective StudiesUltrasonography, PrenatalUterine Cervical IncompetenceConceptsCervical lengthInstitutional review boardProphylactic cerclageShirodkar sutureIncompetent cervixMethods PatientsTerm deliveryTransvaginal ultrasoundObservational studyResults TwentyPhysician preferenceReview boardMcDonald operationsCerclageFurther studiesMeasurable increaseShirodkarCervixPatientsChange in cervical length after prophylactic cerclage.
Funai E, Paidas M, Rebarber A, O'Neill L, Rosen T, Young B. Change in cervical length after prophylactic cerclage. Obstetrics And Gynecology 1999, 94: 117-9. PMID: 10389730, DOI: 10.1016/s0029-7844(98)00568-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultCervix UteriFemaleHumansPregnancyProspective StudiesUltrasonography, PrenatalUterine Cervical Incompetence
1998
Fetal Splenic Size in Anemia Due to Rh-alloimmunization
BAHADO-SINGH R, OZ U, MARI G, JONES D, PAIDAS M, ONDEROGLU L. Fetal Splenic Size in Anemia Due to Rh-alloimmunization. Obstetrics And Gynecology 1998, 92: 828-832. DOI: 10.1097/00006250-199811000-00017.Peer-Reviewed Original ResearchConceptsSevere anemiaPrior transfusionsHemoglobin deficitSplenic enlargementCircumference valuesPrediction of anemiaMean hemoglobin concentrationReceiver operator characteristic curveCross-sectional normative dataOperator characteristic curveSensitized casesSingleton pregnanciesFetal anemiaGestational ageNormal medianRh alloimmunizationSplenic sizeSplenic lengthSingleton fetusesAbdominal circumferenceExtramedullary erythropoiesisFetal abdomenNormal groupAnemiaHemoglobin concentration
1996
Antenatal management of alloimmune thrombocytopenia with intravenous γ-globulin: A randomized trial of the addition of low-dose steroid to intravenous γ-globulin
Bussel J, Berkowitz R, Lynch L, Lesser M, Paidas M, Huang C, McFarland J. Antenatal management of alloimmune thrombocytopenia with intravenous γ-globulin: A randomized trial of the addition of low-dose steroid to intravenous γ-globulin. American Journal Of Obstetrics And Gynecology 1996, 174: 1414-1423. PMID: 9065105, DOI: 10.1016/s0002-9378(96)70582-3.Peer-Reviewed Original ResearchMeSH KeywordsCerebral HemorrhageDexamethasoneDose-Response Relationship, DrugDrug Therapy, CombinationFemaleFetal BloodFetal DiseasesHumansImmunoglobulins, IntravenousIsoantibodiesMaternal-Fetal ExchangePlatelet CountPrednisonePregnancyProspective StudiesSalvage TherapyThrombocytopeniaTreatment OutcomeConceptsIntravenous γ-globulinAlloimmune thrombocytopeniaThrombocytopenic fetusesIntracranial hemorrhageIntravenous gamma globulin treatmentGamma globulin treatmentLow-dose steroidsUtero platelet transfusionsFetal blood samplingMaternal infusionAntenatal managementSevere thrombocytopeniaΓ-globulinPlatelet countPlatelet transfusionsBlood samplingFetal bloodThrombocytopeniaPlatelet increaseDexamethasoneFetusesGm/PrednisoneNonrespondersHemorrhage