2024
Association Between Frailty and Management and Outcomes of Acute Myocardial Infarction Complicated by Cardiogenic Shock
Jamil Y, Park D, Rao S, Ahmad Y, Sikand N, Bosworth H, Coles T, Damluji A, Nanna M, Samsky M. Association Between Frailty and Management and Outcomes of Acute Myocardial Infarction Complicated by Cardiogenic Shock. JACC Advances 2024, 3: 100949. PMID: 38938859, PMCID: PMC11198471, DOI: 10.1016/j.jacadv.2024.100949.Peer-Reviewed Original ResearchAcute myocardial infarctionAMI-CSIn-hospital outcomesDo-not-resuscitate statusPatients admitted with acute myocardial infarctionOdds of in-hospital mortalitySkilled nursing facilityPrevalence of frailtyProportion of hospitalsAssociated with in-hospital outcomesIn-hospital adverse eventsCompare in-hospital outcomesRisk score cut-offNational Inpatient SampleNursing facilitiesIn-hospital mortalityScore cut-offAssociated with adverse outcomesInpatient SampleFrailtyCardiogenic shockIn-hospital morbidityMyocardial infarction complicationsNonfrail groupOddsFrailty and In-Hospital Outcomes for Management of Cardiogenic Shock without Acute Myocardial Infarction
Park D, Jamil Y, Ahmad Y, Coles T, Bosworth H, Sikand N, Davila C, Babapour G, Damluji A, Rao S, Nanna M, Samsky M. Frailty and In-Hospital Outcomes for Management of Cardiogenic Shock without Acute Myocardial Infarction. Journal Of Clinical Medicine 2024, 13: 2078. PMID: 38610842, PMCID: PMC11012362, DOI: 10.3390/jcm13072078.Peer-Reviewed Original ResearchDo-not-resuscitate statusOdds of in-hospital mortalitySkilled nursing facilityIn-hospital adverse eventsRelationship of frailtyCompare in-hospital outcomesNon-frail groupRisk score cut-offNational Inpatient SampleAssociated with increased rates of morbidityNursing facilitiesMyocardial infarctionAssociated with increased ratesFrail adultsIn-hospital mortalityIn-hospital outcomesAcute myocardial infarctionFrail groupScore cut-offFrailtyInpatient SampleCardiogenic shockRisk factorsCardiovascular diseaseHospitalFrailty in the cardiac intensive care unit: assessment and impact
Moumneh M, Jamil Y, Kalra K, Ijaz N, Campbell G, Kochar A, Nanna M, van Diepen S, Damluji A. Frailty in the cardiac intensive care unit: assessment and impact. European Heart Journal Acute Cardiovascular Care 2024, 13: 506-514. PMID: 38525951, PMCID: PMC11214587, DOI: 10.1093/ehjacc/zuae039.Peer-Reviewed Original ResearchCardiac intensive care unitIntensive care unitCardiac intensive care unit admissionCare unitAcute cardiovascular illnessHigher comorbidity burdenAcute cardiovascular conditionsYears of ageOptimal therapyYounger patientsClinical outcomesFrail patientsClinical syndromeComorbidity burdenPhysiological reserveCardiovascular diseasePatientsCardiovascular conditionsGeriatric syndromesCardiovascular illnessFrailtyOlder adultsCognitive functionRole of Cognitive Frailty in Older Adults With Cardiovascular Disease
Ijaz N, Jamil Y, Brown C, Krishnaswami A, Orkaby A, Stimmel M, Gerstenblith G, Nanna M, Damluji A. Role of Cognitive Frailty in Older Adults With Cardiovascular Disease. Journal Of The American Heart Association 2024, 13: e033594. PMID: 38353229, PMCID: PMC11010094, DOI: 10.1161/jaha.123.033594.Peer-Reviewed Original ResearchConceptsCognitive frailtyCardiovascular diseaseDecreased cognitive reserveOlder adult populationCognitive impairmentEvidence of dementiaPresence of cognitive impairmentTargeted intervention studiesSedentary behaviorTobacco usePhysical frailtyOlder adultsGeriatric syndromesIntervention studiesCardiovascular cliniciansFrailtyAdult populationAssociated with poor outcomesCognitive reserveRisk factorsOlder patientsCliniciansPoor outcomeTherapeutic strategiesPathophysiological underpinnings
2021
Moving the Field Forward: Untangling the Impact of Frailty on Patients With Advanced Heart Failure and on Prognosticating Outcomes
Clark KAA, Nanna MG. Moving the Field Forward: Untangling the Impact of Frailty on Patients With Advanced Heart Failure and on Prognosticating Outcomes. Journal Of Cardiac Failure 2021, 28: 775-777. PMID: 34936895, PMCID: PMC9106896, DOI: 10.1016/j.cardfail.2021.12.006.Peer-Reviewed Original Research