2024
Composite branched and linear F-actin maximize myosin-induced membrane shape changes in a biomimetic cell model
Sakamoto R, Murrell M. Composite branched and linear F-actin maximize myosin-induced membrane shape changes in a biomimetic cell model. Communications Biology 2024, 7: 840. PMID: 38987288, PMCID: PMC11236970, DOI: 10.1038/s42003-024-06528-4.Peer-Reviewed Original ResearchMeSH KeywordsActin CytoskeletonActinsActomyosinAnimalsBiomimeticsCell MembraneCell ShapeLiposomesModels, BiologicalMyosinsUnilamellar LiposomesConceptsF-actin networkF-actinF-actin architectureMembrane shape changesCell shape changesActivity of myosinInduce membrane deformationActomyosin contractilityShape changesActin cortexActomyosin cortexGiant unilamellar vesiclesActinMembrane deformationUnilamellar vesiclesCell modelNo-slip boundariesForce generationActomyosinMyosinVesiclesForce transmissionConfinement induces internal flows in adherent cell aggregates
Yousafzai M, Amiri S, Sun Z, Pahlavan , Murrell M. Confinement induces internal flows in adherent cell aggregates. Journal Of The Royal Society Interface 2024, 21: 20240105. PMID: 38774959, PMCID: PMC11285874, DOI: 10.1098/rsif.2024.0105.Peer-Reviewed Original Research
2022
Active Regulation of Pressure and Volume Defines an Energetic Constraint on the Size of Cell Aggregates
Yousafzai M, Yadav V, Amiri S, Errami Y, Amiri S, Murrell M. Active Regulation of Pressure and Volume Defines an Energetic Constraint on the Size of Cell Aggregates. Physical Review Letters 2022, 128: 048103. PMID: 35148133, DOI: 10.1103/physrevlett.128.048103.Peer-Reviewed Original Research
2014
How cells flow in the spreading of cellular aggregates
Beaune G, Stirbat T, Khalifat N, Cochet-Escartin O, Garcia S, Gurchenkov V, Murrell M, Dufour S, Cuvelier D, Brochard-Wyart F. How cells flow in the spreading of cellular aggregates. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 8055-8060. PMID: 24835175, PMCID: PMC4050549, DOI: 10.1073/pnas.1323788111.Peer-Reviewed Original Research
2011
Spreading Dynamics of Biomimetic Actin Cortices
Murrell M, Pontani L, Guevorkian K, Cuvelier D, Nassoy P, Sykes C. Spreading Dynamics of Biomimetic Actin Cortices. Biophysical Journal 2011, 100: 1400-1409. PMID: 21402021, PMCID: PMC3059579, DOI: 10.1016/j.bpj.2011.01.038.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsBiomechanical PhenomenaBiomimetic MaterialsCell MembraneHydrodynamicsLiposomesModels, Biological
2004
The Systems Biology of Glycosylation
Murrell M, Yarema K, Levchenko A. The Systems Biology of Glycosylation. ChemBioChem 2004, 5: 1334-1347. PMID: 15457533, DOI: 10.1002/cbic.200400143.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarbohydratesCell CommunicationEukaryotic CellsGlycosylationHumansModels, BiologicalSignal TransductionSystems BiologyConceptsSystems biologyRegulation of differentiationRegulation of glycosylationEukaryotic cellsBiochemical systems analysisCell regulation processesCell decisionsSignal transductionGlycosylationBiologyRegulation processesRegulationTransductionApoptosisDifferentiationProfound influenceCellsNovel research methodology