Memories reactivated under ketamine are subsequently stronger: A potential pre-clinical behavioral model of psychosis
Honsberger MJ, Taylor JR, Corlett PR. Memories reactivated under ketamine are subsequently stronger: A potential pre-clinical behavioral model of psychosis. Schizophrenia Research 2015, 164: 227-233. PMID: 25728834, PMCID: PMC4409515, DOI: 10.1016/j.schres.2015.02.009.Peer-Reviewed Original ResearchConceptsAberrant prediction errorsShort-term memoryMemory reactivationMemory reconsolidationMemory strengthRelated memoriesContextual memoryDelusional beliefsPrediction errorNMDA antagonist ketamineMemorySystemic ketamineSub-anesthetic dosesHuman subjectsBehavioral modelEnhanced destabilizationBeliefsReconsolidationRodent modelsDelusionsPsychosisSubjectsPrior inhibitionError