2012
VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis
Takiar V, Mistry K, Carmosino M, Schaeren-Wiemers N, Caplan MJ. VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis. American Journal Of Physiology - Cell Physiology 2012, 303: c862-c871. PMID: 22895261, PMCID: PMC3469709, DOI: 10.1152/ajpcell.00338.2011.Peer-Reviewed Original ResearchConceptsRenal cystogenesisPrimary ciliaVectorial solute transportApical vesicle transportConsequence of defectsEpithelial cellsEpithelial cyst formationPolarized organizationRenal epithelial cellsBasolateral markersVesicle transportIntegral proteinsAbsent ciliaCiliary defectsExpression resultsAberrant sortingCiliary morphologyOverexpressing cellsImmunofluorescence analysisCiliaCystogenesisCiliogenesisOverexpressionCyst developmentTransgenic mice
1998
Signals and Mechanisms of Sorting in Epithelial Polarity
Gottardi C, Caplan M. Signals and Mechanisms of Sorting in Epithelial Polarity. Advances In Molecular And Cell Biology 1998, 26: 95-131. PMCID: PMC7147917, DOI: 10.1016/s1569-2558(08)60020-x.Peer-Reviewed Original ResearchPolarized epithelial phenotypePlasma membrane domainsCell type controlPolarized epithelial cellsEpithelial membrane polarityEpithelial polarityPolarized organizationCell biologistsIntracellular organellesEpithelial phenotypeCell typesDistinct compartmentsCell physiologistsSemi-permeable barrierIon transport processesEpithelial cellsType controlsOrganismsCellsElectron microscopic levelOrganellesBiologistsFundamental featuresPhenotypePathway