2020
A cut above (and below): Protein cleavage in the regulation of polycystin trafficking and signaling
Padovano V, Mistry K, Merrick D, Gresko N, Caplan MJ. A cut above (and below): Protein cleavage in the regulation of polycystin trafficking and signaling. Cellular Signalling 2020, 72: 109634. PMID: 32283256, PMCID: PMC7269866, DOI: 10.1016/j.cellsig.2020.109634.Peer-Reviewed Original ResearchConceptsPolycystin-1Polycystin proteinsG proteinsPolycystin-1 proteinProtein maturationTerminal tailObligate stepBiological pathwaysProtein cleavagePhysiological functionsProteolytic siteProteinPathological consequencesAutosomal dominant polycystic kidney diseaseTraffickingDominant polycystic kidney diseasePolycystic kidney diseasePrimary functionCleavageRegulationMaturationGenesMitochondriaValuable insightsPathway
2009
Peanut Induced Dendritic Cell (DC) Maturation and Cytokine Production Is Modulated by the Microbial Components of EMP-123, Leading to Changes in Adaptive Immunity In Vitro
Vickery B, Pochard P, Caplan M, Sampson H, Berin M, Bottomly K. Peanut Induced Dendritic Cell (DC) Maturation and Cytokine Production Is Modulated by the Microbial Components of EMP-123, Leading to Changes in Adaptive Immunity In Vitro. Journal Of Allergy And Clinical Immunology 2009, 123: s211. DOI: 10.1016/j.jaci.2008.12.806.Peer-Reviewed Original Research