2024
Associations Among Sleep, Pain, and Medications for Opioid Use Disorder: a Scoping Review
Hsaio C, DiMeola K, Jegede O, Funaro M, Langstengel J, Yaggi H, Barry D. Associations Among Sleep, Pain, and Medications for Opioid Use Disorder: a Scoping Review. Current Addiction Reports 2024, 1-17. DOI: 10.1007/s40429-024-00606-7.Peer-Reviewed Original ResearchOpioid use disorderOUD severityUse disorderTreatment characteristicsOpioid use disorder treatment settingsTreatment of sleepDosing scheduleDisorder severityOpioidPainWeb of ScienceAssessed patientsCochrane LibraryMeasures of sleepMOUD treatmentCurrent evidenceMOUDSleepSleep disturbanceProvider preferencesPatientsStudy examined sleepDisordersTreatment settingsMedicationThe Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review
Jegede O, De Aquino J, Hsaio C, Caldwell E, Funaro M, Petrakis I, Muvvala S. The Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review. Journal Of Addiction Medicine 2024, 18: 499-510. PMID: 39356620, PMCID: PMC11449257, DOI: 10.1097/adm.0000000000001356.Peer-Reviewed Original ResearchNonmedical opioid useOpioid use disorderOpioid useWithdrawal symptomsTreatment outcomesSymptoms prior to treatmentUse disorderRisk of precipitated withdrawalLow-dose buprenorphineSynthetic opioidsPotency synthetic opioidsConclusions Current evidencePrecipitated withdrawalRisk of overdoseDosing strategiesPharmacological interactionsClinical significanceDecreased riskWeb of ScienceOpioidInclusion criteriaCurrent evidenceClinical implicationsMOUDPain
2021
A systematic review of the association between sleep health and stress biomarkers in children
Ordway MR, Condon EM, Basile Ibrahim B, Abel EA, Funaro MC, Batten J, Sadler LS, Redeker NS. A systematic review of the association between sleep health and stress biomarkers in children. Sleep Medicine Reviews 2021, 59: 101494. PMID: 34098244, PMCID: PMC8458225, DOI: 10.1016/j.smrv.2021.101494.Peer-Reviewed Original ResearchConceptsSleep healthSystematic reviewStress biomarkersStress response systemEarly childhoodChildren ages 0Evidence of associationRole of sleepMetabolic outcomesSchool-aged childrenCurrent evidencePRISMA guidelinesNeuroendocrine variablesPhysiologic stressMajority of studiesSleep dimensionsSleepAges 0BiomarkersLongitudinal studyYoung childrenChildrenObjective measuresHealthAdult literatureA systematic review of ketamine for the treatment of depression among older adults
Farheen S, Gupta A, Dhar R, Patadia P, Funaro M, Bhattacharya G, Tampi R. A systematic review of ketamine for the treatment of depression among older adults. American Journal Of Geriatric Psychiatry 2021, 29: s93-s96. DOI: 10.1016/j.jagp.2021.01.089.Peer-Reviewed Educational MaterialsPrimary outcome measureUse of ketamineLate-life depressionTreatment of depressionOlder adultsElectroconvulsive therapyReceptor antagonistLife depressionOutcome measuresCurrent evidenceDepressive symptomsOlder subjectsHamilton Depression Rating Scale scoresN-methyl-D-aspartate receptor antagonistSystematic reviewStudy participantsDepression Rating Scale scoresAdverse effectsBenefits of ketamineTolerability of ketamineCognitive adverse effectsCochrane Central RegisterTreatment-resistant depressionAnti-depressant effectsRelapse of symptomsIs there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults?
Bhattacharya G, Gupta A, Joshi P, Lehman M, Funaro M, Tampi D, Tampi R. Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults? American Journal Of Geriatric Psychiatry 2021, 29: s136-s139. DOI: 10.1016/j.jagp.2021.01.131.Peer-Reviewed Educational MaterialsTreatment of deliriumRandomized control trialTotal knee replacementTotal hip replacementValproic acid preparationsPostoperative deliriumValproic acid derivativesPerioperative useSpinal surgeryOlder adultsCurrent evidenceElective total knee replacementElective total hip replacementAverage medical care costAcute neuropsychiatric syndromeCauses of deliriumUse of gabapentinManagement of deliriumNon-pharmacological strategiesCochrane Central RegisterNon-pharmacologic treatmentsHospitalized older adultsUse of anticonvulsantsIntensive care unitPalliative care settingIs there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults?
Gupta A, Joshi P, Bhattacharya G, Lehman M, Funaro M, Tampi DJ, Tampi RR. Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults? International Psychogeriatrics 2021, 34: 889-903. PMID: 33757611, DOI: 10.1017/s1041610221000235.Peer-Reviewed Educational MaterialsConceptsTreatment of deliriumTotal knee arthroplastyTotal hip arthroplastyPostoperative deliriumUse of anticonvulsantsPerioperative useSpinal surgeryOlder adultsElective total knee arthroplastyElective total hip arthroplastyUse of gabapentinCochrane Central RegisterAnalysis of RCTsPerioperative gabapentinCentral RegisterKnee arthroplastyHip arthroplastyDeliriumCurrent evidenceGabapentinRCTsAnticonvulsantsSystematic reviewArthroplastyComprehensive search
2020
A systematic review of ketamine for the treatment of depression among older adults
Gupta A, Dhar R, Patadia P, Funaro M, Bhattacharya G, Farheen SA, Tampi RR. A systematic review of ketamine for the treatment of depression among older adults. International Psychogeriatrics 2020, 33: 179-191. PMID: 32600480, DOI: 10.1017/s1041610220000903.Peer-Reviewed Educational MaterialsConceptsUse of ketaminePrimary outcome measureTreatment of depressionOlder adultsAdverse effectsOutcome measuresMontgomery-Asberg Depression Rating Scale scoreDepression Rating Scale scoresBenefits of ketamineCognitive adverse effectsRating Scale scoresEsketamine groupPlacebo groupRemission rateIntranasal ketamineKetamine administrationMADRS scoresInclusion criteriaDepressive symptomsCurrent evidenceScale scoreDepression symptomsKetamineSystematic reviewNegative trials