Atypical presentations of carboplatin hypersensitivity reactions: Characterization and management in patients with gynecologic malignancies
McAlpine JN, Kelly MG, O'Malley DM, Azodi M, Coombe K, Schwartz PE, Rutherford TJ. Atypical presentations of carboplatin hypersensitivity reactions: Characterization and management in patients with gynecologic malignancies. Gynecologic Oncology 2006, 103: 288-292. PMID: 16647749, DOI: 10.1016/j.ygyno.2006.03.007.Peer-Reviewed Original ResearchConceptsSkin testingPlatinum hypersensitivityAllergy symptomsCarboplatin cycleLife-threatening adverse eventsCarboplatin skin testingCarboplatin-treated patientsCycles/patientDuration of symptomsRetrospective chart reviewSystemic allergic reactionsCarboplatin hypersensitivity reactionsContinuation of treatmentNegative predictive valueAPH patientsChart reviewChemotherapeutic cyclesGynecologic malignanciesAdverse eventsAtypical presentationDose escalationMedian onsetHypersensitivity reactionsAllergic reactionsMedian number