2020
Introduction to the Physiology, Immunology and Pathology of the Liver and Biliary Tree
Carbone M, Strazzabosco M. Introduction to the Physiology, Immunology and Pathology of the Liver and Biliary Tree. 2020, 3-20. DOI: 10.1002/9781119532637.ch1.Peer-Reviewed Original ResearchBile acidsBile formationDietary lipid absorptionMetabolism of bilirubinBiliary tree stem cellsBiliary treeLiver synthesisHepatic metabolismLipid absorptionEnergy homeostasisCholesterol homeostasisMetabolic homeostasisLiverCanalicular secretionStem cellsSecretionHomeostasisRegenerative abilityMetabolismBilirubinPathologyEndotoxinImmunology
2015
Emerging roles of Notch signaling in liver disease
Geisler F, Strazzabosco M. Emerging roles of Notch signaling in liver disease. Hepatology 2015, 61: 382-392. PMID: 24930574, PMCID: PMC4268103, DOI: 10.1002/hep.27268.Peer-Reviewed Original ResearchConceptsRole of NotchNotch signalingMammalian cell fateSpecific cellular contextCell fateCellular contextOrgan homeostasisStem cell featuresSignificance of NotchDistinct liver cell typesLiver developmentLiver cell typesCell typesLiver diseaseIntrahepatic cholangiocarcinomaLiver malignanciesHepatocellular carcinomaFurther cellHomeostasisLiver homeostasisLiver metabolismPersistent activationClinical practiceRepair processSignaling