2017
Maternal smoking and autism spectrum disorder: meta-analysis with population smoking metrics as moderators
Jung Y, Lee AM, McKee SA, Picciotto MR. Maternal smoking and autism spectrum disorder: meta-analysis with population smoking metrics as moderators. Scientific Reports 2017, 7: 4315. PMID: 28659613, PMCID: PMC5489536, DOI: 10.1038/s41598-017-04413-1.Peer-Reviewed Original ResearchConceptsMale smoking prevalenceMaternal smokingNicotine exposureSmoking prevalenceAdult male smoking prevalenceSignificant associationPostnatal nicotine exposureUtero nicotine exposureAutism spectrum disorderRandom-effects modelWorld Health Organization dataMeta-regression analysisSmoking metricsSmoke exposureSecondhand smokingPooled ORsObservational studySpectrum disorderSmokingBrain developmentControl participantsPrevalenceASD riskExposureAssociation
2012
Impaired auditory discrimination learning following perinatal nicotine exposure or β2 nicotinic acetylcholine receptor subunit deletion
Horst NK, Heath CJ, Neugebauer NM, Kimchi EY, Laubach M, Picciotto MR. Impaired auditory discrimination learning following perinatal nicotine exposure or β2 nicotinic acetylcholine receptor subunit deletion. Behavioural Brain Research 2012, 231: 170-180. PMID: 22433585, PMCID: PMC3334440, DOI: 10.1016/j.bbr.2012.03.002.Peer-Reviewed Original ResearchConceptsAuditory stimulus processingStimulus processingAuditory discrimination learningUnderlying neurobiological mechanismsAuditory discrimination paradigmLow rates (DRL) taskPerinatal nicotine exposureAuditory discriminationGeneral deficitDiscrimination learningTask performanceNicotine exposureDiscrimination impairmentNeurobiological mechanismsMouse perinatal developmentDiscrimination paradigmRate taskDifferential reinforcementAdministration of nicotineTaskAuditory pathwayLearningNicotinic acetylcholine receptorsMaternal smokingProcessing
2007
Prenatal and Adolescent Exposure to Tobacco Smoke Modulates the Development of White Matter Microstructure
Jacobsen LK, Picciotto MR, Heath CJ, Frost SJ, Tsou KA, Dwan RA, Jackowski MP, Constable RT, Mencl WE. Prenatal and Adolescent Exposure to Tobacco Smoke Modulates the Development of White Matter Microstructure. Journal Of Neuroscience 2007, 27: 13491-13498. PMID: 18057207, PMCID: PMC6673092, DOI: 10.1523/jneurosci.2402-07.2007.Peer-Reviewed Original ResearchConceptsAuditory processingAdolescent exposureWhite matter microstructureAuditory attention taskSymptoms of inattentionAuditory processing deficitsNicotine-induced disruptionAuditory attentionAttention taskPrenatal exposureProcessing deficitsAuditory signalsAdolescent smokersAdolescent smokingTobacco smokeFractional anisotropyDiffusion tensor anisotropyMaternal smokingCorticofugal fibersInternal capsuleParent educationDevelopmental disruptionReaction timeInternal capsule fibersAnatomical magnetic resonance images