2021
Renalase is a novel tissue and serological biomarker in pancreatic ductal adenocarcinoma
Gao Y, Wang M, Guo X, Hu J, Chen TM, Finn S, Lacy J, Kunstman JW, H. C, Bellin MD, Robert ME, Desir GV, Gorelick FS. Renalase is a novel tissue and serological biomarker in pancreatic ductal adenocarcinoma. PLOS ONE 2021, 16: e0250539. PMID: 34587190, PMCID: PMC8480607, DOI: 10.1371/journal.pone.0250539.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkers, TumorCarcinoma, Pancreatic DuctalCase-Control StudiesFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedMonoamine OxidaseNeoplasm GradingPancreatic NeoplasmsPrognosisProspective StudiesRetrospective StudiesSurvival AnalysisUp-RegulationYoung AdultConceptsPlasma renalase levelsBorderline resectable PDACRenalase levelsPDAC precursor lesionsOverall survivalPDAC tissuesTumor characteristicsResectable PDACChronic pancreatitisPrecursor lesionsNormal pancreasPancreatic ductal adenocarcinoma growthAdvanced tumor characteristicsVaried clinical stagesWorse tumor characteristicsNode-positive diseasePancreatic ductal adenocarcinomaNormal pancreatic headSpindle-shaped cellsPlasma renalaseRenalase expressionUnderwent resectionAbdominal traumaPancreatic headPositive disease
1995
PERFORIN AND GRANZYME B
McDiarmid S, Farmer D, Kuniyoshi J, Robert M, Khadavi A, Shaked A, Busuttil R. PERFORIN AND GRANZYME B. Transplantation 1995, 59: 762-766. PMID: 7886805, DOI: 10.1097/00007890-199503150-00021.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceBiomarkersBlotting, SouthernCytokinesGraft RejectionGranzymesIntestine, SmallMembrane GlycoproteinsMolecular Sequence DataPerforinPore Forming Cytotoxic ProteinsRatsRats, Inbred BNRats, Inbred LewRNA, MessengerSerine EndopeptidasesT-Lymphocytes, CytotoxicTransplantation, HomologousUp-RegulationConceptsGranzyme BLewis recipientsAllograft groupIsograft controlsPostoperative day 3Reverse transcriptase-polymerase chain reaction methodSemiquantitative reverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reaction methodReverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionHistologic rejectionPOD 14Transplant allograftsMild rejectionPOD 3POD 5Killer cellsPOD 10Polymerase chain reaction methodHistologic evidenceTransplant rejectionPolymerase chain reactionF1 donorsHistologic evaluationChain reaction method
1994
THE CORRELATION OF INTRAGRAFT CYTOKINE EXPRESSION WITH REJECTION IN RAT SMALL INTESTINE TRANSPLANTATION
McDIARMID S, FARMER D, KUNIYOSHI J, ROBERT M, KHADAVI A, SHAKED A, BUSUTTIL R. THE CORRELATION OF INTRAGRAFT CYTOKINE EXPRESSION WITH REJECTION IN RAT SMALL INTESTINE TRANSPLANTATION. Transplantation 1994, 58: 690-697. PMID: 7940688, DOI: 10.1097/00007890-199409270-00009.Peer-Reviewed Original ResearchConceptsSmall intestine transplantationInterleukin-6Reverse transcriptase-PCRTNF-alphaInterleukin-2IFN-gammaPOD 14POD 3POD 7Cytokine expressionTumor necrosis factor alphaIntragraft cytokine expressionSeverity of rejectionEvidence of rejectionIL-2 receptorNecrosis factor alphaSemiquantitative reverse transcriptase-PCRRat small intestineExpression of mRNAIntestine transplantationGraft lossLewis recipientsHistologic rejectionIntragraft expressionMild rejection