1995
PERFORIN AND GRANZYME B
McDiarmid S, Farmer D, Kuniyoshi J, Robert M, Khadavi A, Shaked A, Busuttil R. PERFORIN AND GRANZYME B. Transplantation 1995, 59: 762-766. PMID: 7886805, DOI: 10.1097/00007890-199503150-00021.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceBiomarkersBlotting, SouthernCytokinesGraft RejectionGranzymesIntestine, SmallMembrane GlycoproteinsMolecular Sequence DataPerforinPore Forming Cytotoxic ProteinsRatsRats, Inbred BNRats, Inbred LewRNA, MessengerSerine EndopeptidasesT-Lymphocytes, CytotoxicTransplantation, HomologousUp-RegulationConceptsGranzyme BLewis recipientsAllograft groupIsograft controlsPostoperative day 3Reverse transcriptase-polymerase chain reaction methodSemiquantitative reverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reaction methodReverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionHistologic rejectionPOD 14Transplant allograftsMild rejectionPOD 3POD 5Killer cellsPOD 10Polymerase chain reaction methodHistologic evidenceTransplant rejectionPolymerase chain reactionF1 donorsHistologic evaluationChain reaction method
1994
THE CORRELATION OF INTRAGRAFT CYTOKINE EXPRESSION WITH REJECTION IN RAT SMALL INTESTINE TRANSPLANTATION
McDIARMID S, FARMER D, KUNIYOSHI J, ROBERT M, KHADAVI A, SHAKED A, BUSUTTIL R. THE CORRELATION OF INTRAGRAFT CYTOKINE EXPRESSION WITH REJECTION IN RAT SMALL INTESTINE TRANSPLANTATION. Transplantation 1994, 58: 690-697. PMID: 7940688, DOI: 10.1097/00007890-199409270-00009.Peer-Reviewed Original ResearchConceptsSmall intestine transplantationInterleukin-6Reverse transcriptase-PCRTNF-alphaInterleukin-2IFN-gammaPOD 14POD 3POD 7Cytokine expressionTumor necrosis factor alphaIntragraft cytokine expressionSeverity of rejectionEvidence of rejectionIL-2 receptorNecrosis factor alphaSemiquantitative reverse transcriptase-PCRRat small intestineExpression of mRNAIntestine transplantationGraft lossLewis recipientsHistologic rejectionIntragraft expressionMild rejectionIntragraft Expression of Messenger RNA for Interleukin-6 and Tumor Necrosis Factor-α Is a Predictor of Rat Small Intestine Transplant Rejection
Farmer D, McDiarmid S, Kuniyoshi J, Robert M, Shaked A, Busuttil R. Intragraft Expression of Messenger RNA for Interleukin-6 and Tumor Necrosis Factor-α Is a Predictor of Rat Small Intestine Transplant Rejection. Journal Of Surgical Research 1994, 57: 138-142. PMID: 8041128, DOI: 10.1006/jsre.1994.1121.Peer-Reviewed Original ResearchConceptsSmall intestine transplantationInterleukin-6Intragraft expressionPOD 5MRNA expressionIL-6 mRNA expressionRTPCR analysisDetection of rejectionMessenger RNAPostoperative day 3Interleukin-2 receptorTumor necrosis factorUseful diagnostic adjunctTranscriptase-polymerase chain reactionBeta-scintillation countingIntestine transplantationIntestinal histopathologyPOD 8Transplant rejectionPolymerase chain reactionTumor necrosisIL-2RNecrosis factorAllograftsDiagnostic adjunctIntragraft cytokine and cytotoxic T lymphocyte (CTL) specific protein expression as predictors of rat small intestine transplant rejection.
McDiarmid S, Farmer D, Kuniyoshi J, Robert M, Khadavi A, Shaked A, Busuttil R. Intragraft cytokine and cytotoxic T lymphocyte (CTL) specific protein expression as predictors of rat small intestine transplant rejection. Transplantation Proceedings 1994, 26: 1520-1. PMID: 8030018.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersCytokinesGraft RejectionInterferon-gammaInterleukin-2Interleukin-6Intestine, SmallMembrane GlycoproteinsPerforinPolymerase Chain ReactionPore Forming Cytotoxic ProteinsRatsRats, Inbred BNRats, Inbred LewReceptors, Interleukin-2RNA, MessengerSerine EndopeptidasesT-Lymphocytes, CytotoxicTime FactorsTransplantation, HomologousTransplantation, IsogeneicTumor Necrosis Factor-alpha