Dysplasia as a predictive marker for invasive carcinoma in Barrett esophagus: A follow-up study based on 138 cases from a diagnostic variability study
Montgomery E, Goldblum J, Greenson J, Haber M, Lamps L, Lauwers G, Lazenby A, Lewin D, Robert M, Washington K, Zahurak M, Hart J. Dysplasia as a predictive marker for invasive carcinoma in Barrett esophagus: A follow-up study based on 138 cases from a diagnostic variability study. Human Pathology 2001, 32: 379-388. PMID: 11331954, DOI: 10.1053/hupa.2001.23511.Peer-Reviewed Original ResearchConceptsHigh-grade dysplasiaLow-grade dysplasiaBarrett's esophagusInvasive carcinomaMajority diagnosisCases of HGDCases of LGDCases of BEEndoscopic biopsy specimensKaplan-Meier statisticsInitial biopsyEndoscopic surveillanceUlcerated areaGastrointestinal pathologyBiopsy specimenPredictive markerBiopsy diagnosisBiopsy specimensIntramucosal carcinomaPrecursor lesionsIND casesPowerful prognosticatorCarcinomaMorphologic evaluationUlcerated casesReproducibility of the diagnosis of dysplasia in Barrett esophagus: A reaffirmation
Montgomery E, Bronner M, Goldblum J, Greenson J, Haber M, Hart J, Lamps L, Lauwers G, Lazenby A, Lewin D, Robert M, Toledano A, Shyr Y, Washington K. Reproducibility of the diagnosis of dysplasia in Barrett esophagus: A reaffirmation. Human Pathology 2001, 32: 368-378. PMID: 11331953, DOI: 10.1053/hupa.2001.23510.Peer-Reviewed Original ResearchConceptsLow-grade dysplasiaHigh-grade dysplasiaDiagnosis of dysplasiaConsensus meetingBarrett's esophagusInterobserver agreementIntraobserver kappaDiagnostic categoriesModified grading systemKappa statisticsBasis of treatmentBroad diagnostic categoriesBarrett's mucosaPrior diagnosisGastrointestinal pathologistsConsensus conferenceInterobserver kappaDysplasiaMorphologic assessmentGrading systemStatistical analysisInterobserver reproducibilityIntraobserver reproducibilityDiagnosis