2023
Clinical Data Do Not Reliably Predict Duodenal Histology at Follow-up in Celiac Disease
Patel N, Leffler D, Al-Toma A, Mulder C, Elli L, Gan G, Patil P, Atsawarungruangkit A, Kuijpers K, Del Gobbo A, Goldsmith J, Hintze Z, Pacheco M, Vieth M, Melcher B, Salomao M, Pai R, Hart J, Olivas A, Naini B, Meyerson C, Choi W, Kakar S, Westerhoff M, Cheng J, Gopal P, Hammer S, Prats M, Bronner M, Robert M. Clinical Data Do Not Reliably Predict Duodenal Histology at Follow-up in Celiac Disease. The American Journal Of Surgical Pathology 2023, 48: 212-220. PMID: 37994653, DOI: 10.1097/pas.0000000000002150.Peer-Reviewed Original ResearchIntraepithelial lymphocytesCeliac diseaseClinical dataMarsh scoreMucosal recoveryVillous bluntingDuodenal biopsiesMucosal injuryDiet adherenceGluten-free diet adherenceComplete histologic remissionPersistent mucosal injuryMinority of patientsCeliac disease patientsDuodenal histologyHistologic remissionPathologists' awarenessMucosal statusMucosal healingGastrointestinal pathologistsDisease patientsFollow-upPatient managementEligibility criteriaPatients
1996
Rectal afferent function in patients with inflammatory and functional intestinal disorders
Bernstein C, Niazi N, Robert M, Mertz H, Kodner A, Munakata J, Naliboff B, Mayer E. Rectal afferent function in patients with inflammatory and functional intestinal disorders. Pain 1996, 66: 151-161. PMID: 8880836, DOI: 10.1016/0304-3959(96)03062-x.Peer-Reviewed Original ResearchConceptsIrritable bowel syndromeInflammatory bowel diseaseDiarrhea-predominant irritable bowel syndromeViscerosomatic referral patternCrohn's disease patientsIBS patientsDisease patientsCrohn's diseaseMale patientsReferral patternsAfferent pathwaysReflex responsesHealthy male control subjectsTissue irritationAutonomic reflex responsesChronic ileal inflammationLower distension pressuresRapid phasic distensionDorsal horn neuronsVisceral afferent pathwaysIleal Crohn's diseaseFunctional intestinal disordersMale control subjectsSkin conductance responsesBulbospinal inhibition
1993
Rectal substance P concentrations are increased in ulcerative colitis but not in Crohn's disease.
Bernstein C, Robert M, Eysselein V. Rectal substance P concentrations are increased in ulcerative colitis but not in Crohn's disease. The American Journal Of Gastroenterology 1993, 88: 908-13. PMID: 7684884.Peer-Reviewed Original ResearchConceptsSubstance P concentrationsSubstance P levelsCrohn's diseaseUlcerative colitisSubstance PIncreasing concentrations of substance PConcentrations of substance PPathogenesis of ulcerative colitisRectal mucosal biopsiesNon-inflammatory bowel disease patientsMucosal neutrophilsUC patientsMucosal levelMucosal biopsiesCD patientsAffected patientsIncreased inflammationInflammatory cellsRectal diseaseColonic mucosaInflammatory processPatientsDisease patientsBiopsyMotor phenomena