2014
A Cluster-Randomized Controlled Trial of a Multicomponent Intervention Protocol for Pneumonia Prevention Among Nursing Home Elders
Juthani-Mehta M, Van Ness PH, McGloin J, Argraves S, Chen S, Charpentier P, Miller L, Williams K, Wall D, Baker D, Tinetti M, Peduzzi P, Quagliarello VJ. A Cluster-Randomized Controlled Trial of a Multicomponent Intervention Protocol for Pneumonia Prevention Among Nursing Home Elders. Clinical Infectious Diseases 2014, 60: 849-857. PMID: 25520333, PMCID: PMC4415071, DOI: 10.1093/cid/ciu935.Peer-Reviewed Original ResearchConceptsNursing home residentsUsual careHome residentsIntervention protocolFirst pneumoniaControl armClinical trialsNursing homesMultivariable Cox regression modelsElderly nursing home residentsCluster-randomized clinical trialImportant public health problemChlorhexidine oral rinseModifiable risk factorsRespiratory tract infectionsCox regression modelNursing home eldersPublic health problemHazard ratioPneumonia preventionSecondary outcomesTract infectionsControlled TrialsPrimary outcomeOral rinse
2010
Infectious Diseases in the Nursing Home Setting: Challenges and Opportunities for Clinical Investigation
High K, Juthani-Mehta M, Quagliarello V. Infectious Diseases in the Nursing Home Setting: Challenges and Opportunities for Clinical Investigation. Clinical Infectious Diseases 2010, 51: 931-936. PMID: 20822459, PMCID: PMC3083824, DOI: 10.1086/656411.Peer-Reviewed Original ResearchConceptsNursing home residentsHome residentsInfectious diseasesNursing homesNursing home settingMultiple comorbid diseasesPublic health problemComorbid diseasesHigh prevalenceFunctional declineClinical investigationPhysician investigatorsHealth problemsDiseaseHome settingOlder AmericansUnique issuesResidentsImmunosenescencePrognosisDementiaInfectionPrevalenceDiagnosis