Nuclear filaments: role in chromosomal positioning and gene expression
Bera M, Sengupta K. Nuclear filaments: role in chromosomal positioning and gene expression. Nucleus 2020, 11: 99-110. PMID: 32453974, PMCID: PMC7529408, DOI: 10.1080/19491034.2020.1769445.Peer-Reviewed Original ResearchConceptsChromosomal contactsGene expressionLMNA mutationsInner nuclear membraneDNA damage repairGene expression profilesIntrachromosomal contactsChromosomal positioningChromosome positioningNuclear actinNuclear laminsEpigenetic modificationsLamin networkChromosomal loopsDamage repairExpression profilesNuclear membraneNuclear processesKey playersLaminsLaminopathiesMutationsElastic meshworkMuscle tissueMechanical rigidity