Mathematical Model for the Natural History of Human Papillomavirus Infection and Cervical Carcinogenesis
Myers E, McCrory D, Nanda K, Bastian L, Matchar D. Mathematical Model for the Natural History of Human Papillomavirus Infection and Cervical Carcinogenesis. American Journal Of Epidemiology 2000, 151: 1158-1171. PMID: 10905528, DOI: 10.1093/oxfordjournals.aje.a010166.Peer-Reviewed Original ResearchConceptsHuman papillomavirus infectionSquamous intraepithelial lesionsNatural historyHPV infectionPapillomavirus infectionIntraepithelial lesionsHigh-grade squamous intraepithelial lesionsCervical cancer stage ILifetime cervical cancer riskAge-specific incidence ratesCervical cancer carcinogenesisCervical cancer incidenceCancer stage ISecondary prevention strategiesCervical cancer riskHigh-grade lesionsAge 50 yearsAge-specific incidenceCancer mortality riskCohort of womenAge-specific distributionNatural history parametersCervical cancerPeak incidenceCervical cytology