Screening of blood donors for sickle cell trait using a DNA‐based approach: Frequency in a multiethnic donor population
Gowda L, Vege S, Kessler D, Shaz B, Westhoff CM. Screening of blood donors for sickle cell trait using a DNA‐based approach: Frequency in a multiethnic donor population. Transfusion 2021, 61: 2008-2013. PMID: 33929058, DOI: 10.1111/trf.16403.Peer-Reviewed Original ResearchMeSH KeywordsAdultBeta-GlobinsBlood DonorsChromatography, High Pressure LiquidDNADonor SelectionEthnicityFemaleHemoglobin, SickleHumansMaleMinority GroupsNew York CityRetrospective StudiesSequence Analysis, DNASickle Cell TraitSolubilityConceptsSickle cell traitCell traitHigh-performance liquid chromatographyTesting of donorsSpecific patient groupsSickle cell diseaseHuman erythrocyte antigensTransfusion needsPatient groupBlood donorsCell diseaseRepeat testingRandom donorsScreen donorsGene sequencingDonor recordsErythrocyte antigensDonor populationHb screeningHemoglobin solubilityRBC donorsGold standardScreening resultsNegative resultsHemoglobin variation