2020
Hematopoietic cell transplantation utilization and outcomes for primary plasma cell leukemia in the current era
Dhakal B, Patel S, Girnius S, Bachegowda L, Fraser R, Davila O, Kanate AS, Assal A, Hanbali A, Bashey A, Pawarode A, Freytes CO, Lee C, Vesole D, Cornell RF, Hildebrandt GC, Murthy HS, Lazarus HM, Cerny J, Yared JA, Schriber J, Berdeja J, Stockerl-Goldstein K, Meehan K, Holmberg L, Solh M, Diaz MA, Kharfan-Dabaja MA, Farhadfar N, Bashir Q, Munker R, Olsson RF, Gale RP, Bayer RL, Seo S, Chhabra S, Hashmi S, Badawy SM, Nishihori T, Gonsalves W, Nieto Y, Efebera Y, Kumar S, Shah N, Qazilbash M, Hari P, D’Souza A. Hematopoietic cell transplantation utilization and outcomes for primary plasma cell leukemia in the current era. Leukemia 2020, 34: 3338-3347. PMID: 32313109, PMCID: PMC7572530, DOI: 10.1038/s41375-020-0830-0.Peer-Reviewed Original ResearchConceptsPrimary plasma cell leukemiaHematopoietic cell transplantationKarnofsky performance statusPlasma cell leukemiaAllo-HCTPPCL patientsCell leukemiaNovel agent eraGood partial responseOutcomes of patientsHigh relapse rateAgent eraHCT utilizationSuperior OSPartial responsePerformance statusInferior survivalMedian ageRelapse rateCell transplantationSEER dataMortality 7Multi-variate analysisPatientsSurvival 17
2019
Primary Plasma Cell Leukemia Outcomes Remain Dismal Despite Novel Agents and Hematopoietic Cell Transplantation
Patel S, Girnius S, Dhakal B, Gowda L, Fraser R, Davila O, Shah N, Qazilbash M, Kumar S, D'Souza A, Hari P. Primary Plasma Cell Leukemia Outcomes Remain Dismal Despite Novel Agents and Hematopoietic Cell Transplantation. Blood 2019, 134: 266. DOI: 10.1182/blood-2019-127049.Peer-Reviewed Original ResearchPrimary plasma cell leukemiaNon-relapse mortalityHematopoietic cell transplantationProgression-free survivalHigh-risk cytogeneticsMonths of diagnosisRelapse/progressionPPCL patientsOverall survivalMedian ageCell transplantationNovel agentsDisease statusLower non-relapse mortalityRare plasma cell neoplasmAdvisory CommitteeMultiple myeloma's (MM) outcomePost-HCT outcomesKarnofsky performance scoreSpeakers bureauSuperior overall survivalTotal body irradiationMarrow Transplant ResearchPlasma cell leukemiaPlasma cell neoplasms