A bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase
Cullati SN, Kabeche L, Kettenbach AN, Gerber SA. A bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase. Journal Of Cell Biology 2017, 216: 2339-2354. PMID: 28630147, PMCID: PMC5551695, DOI: 10.1083/jcb.201512055.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnaphaseChromatography, AffinityCytokinesisHeLa CellsHumansHydrolysisIntracellular Signaling Peptides and ProteinsKinesinsNIMA-Related KinasesOncogene ProteinsPhosphorylationProtein Serine-Threonine KinasesRNA InterferenceSignal TransductionSpindle ApparatusTandem Mass SpectrometryTime FactorsTransfectionConceptsProtein-protein interactionsAnaphase central spindleNEK kinasesKinase NEK6Distinct kinesinsBundling activityPosttranslational modificationsCentral spindleCytoskeletal structuresNek9MKlp2Genetic materialTimely localizationKinesinCytokinesisNEK6Sophisticated networkKinaseNIMANEK7KIF14CascadeAnaphaseLocalizationMidzone