2022
Brainstem serotonin neurons selectively gate retinal information flow to thalamus
Reggiani J, Jiang Q, Barbini M, Lutas A, Liang L, Fernando J, Deng F, Wan J, Li Y, Chen C, Andermann M. Brainstem serotonin neurons selectively gate retinal information flow to thalamus. Neuron 2022, 111: 711-726.e11. PMID: 36584680, PMCID: PMC10131437, DOI: 10.1016/j.neuron.2022.12.006.Peer-Reviewed Original ResearchConceptsVisual information streamsRetinal ganglion cell typesBrainstem serotonin neuronsFiber photometry recordingsGanglion cell typesTwo-photon calcium imagingSerotonin neuronsVisual thalamusGlutamate releaseSerotonergic axonsRGC axonsSerotonin axonsThalamocortical neuronsAxon stimulationAwake micePresynaptic terminalsCalcium imagingOptogenetic stimulationCalcium activityLocal visual stimuliAxonsThalamusBoutonsVisual stimuliNeuronsMating-driven variability in olfactory local interneuron wiring
Chou YH, Yang CJ, Huang HW, Liou NF, Panganiban MR, Luginbuhl D, Yin Y, Taisz I, Liang L, Jefferis GSXE, Luo L. Mating-driven variability in olfactory local interneuron wiring. Science Advances 2022, 8: eabm7723. PMID: 35179957, PMCID: PMC8856614, DOI: 10.1126/sciadv.abm7723.Peer-Reviewed Original Research
2020
Organization, Function, and Development of the Mouse Retinogeniculate Synapse
Liang L, Chen C. Organization, Function, and Development of the Mouse Retinogeniculate Synapse. Annual Review Of Vision Science 2020, 6: 261-285. PMID: 32936733, DOI: 10.1146/annurev-vision-121219-081753.Peer-Reviewed Original ResearchConceptsRetinogeniculate synapseDistinct retinal ganglion cell typesRetinal ganglion cell typesGanglion cell typesImage-forming pathwayVisual thalamusThalamocortical neuronsVisual pathwayExperimental modelCircuit organizationThalamusSynapseMiceCell typesFunctional organizationRecent studiesPowerful experimental modelCurrent understandingVisual spaceVisual experiencePathwayNeuronsRGCs
2013
GABAergic Projection Neurons Route Selective Olfactory Inputs to Specific Higher-Order Neurons
Liang L, Li Y, Potter CJ, Yizhar O, Deisseroth K, Tsien RW, Luo L. GABAergic Projection Neurons Route Selective Olfactory Inputs to Specific Higher-Order Neurons. Neuron 2013, 79: 917-931. PMID: 24012005, PMCID: PMC3838762, DOI: 10.1016/j.neuron.2013.06.014.Peer-Reviewed Original ResearchConceptsLateral horn neuronsInhibitory projection neuronsInnate olfactory behaviorsInhibitory tonePresynaptic inhibitionDrosophila olfactory systemHigher-order neuronsProjection neuronsAxon terminalsAntennal lobe glomeruliLateral hornConnection specificityDetectable suppressionOlfactory inputOdor responsesNeuronsOlfactory informationOlfactory systemHigher centersParallel inhibitionDifferential effectsDownstream circuitsInhibition motifCircuit motifsInhibition