2024
Total Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. Total Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events. The Journal Of Arthroplasty 2024, 39: 2421-2426. PMID: 38838962, DOI: 10.1016/j.arth.2024.05.083.Peer-Reviewed Original ResearchFactor V LeidenAdverse eventsChemoprophylactic agentV LeidenMultivariate analysisFactor V Leiden patientsTotal hip arthroplastyPatients to venous thromboembolismLog-rank testIncreased VTE riskVenous thromboembolic eventsElevated riskPerioperative adverse eventsPre-existing comorbiditiesAdministrative claims databaseInherited thrombophiliaThromboembolic eventsElixhauser Comorbidity IndexAdult patientsVenous thromboembolismImplant survivalVTE riskComorbidity indexClaims databaseHip arthroplasty
2023
Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications
Halperin S, Dhodapkar M, Radford Z, Kaszuba S, Rubin L, Grauer J. Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 32: 309-315. PMID: 38165956, DOI: 10.5435/jaaos-d-23-00783.Peer-Reviewed Original ResearchTotal knee arthroplastyTotal hip arthroplastyUrinary tract infectionPostoperative eventsCystic fibrosisPerioperative outcomesAdverse eventsTract infectionsPleural effusionKnee arthroplastyControl subjectsRevision rateAcute kidney injuryElixhauser Comorbidity IndexRisk of surgeryMultivariable logistic regressionComorbidity indexKidney injuryPerioperative complicationsRespiratory failureTKA patientsCardiac eventsPearlDiver databaseImplant survivalTotal hip
2022
Total Hip Arthroplasty in Patients With Classic Hemophilia: A Matched Comparison of 90-Day Outcomes and 5-Year Implant Survival
Gillinov SM, Burroughs PJ, Moore HG, Rubin LE, Frumberg DB, Grauer JN. Total Hip Arthroplasty in Patients With Classic Hemophilia: A Matched Comparison of 90-Day Outcomes and 5-Year Implant Survival. The Journal Of Arthroplasty 2022, 37: 1333-1337. PMID: 35257821, PMCID: PMC9177736, DOI: 10.1016/j.arth.2022.02.107.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyNon-hemophilia patientsMinor adverse eventsSerious adverse eventsAdverse eventsClassic hemophiliaHaemophilia patientsImplant survivalHip arthroplastyGreater oddsMultivariate analysisFive-year implant survivalPrimary total hip arthroplastyAcute kidney injuryVenous thromboembolism prophylaxisElixhauser Comorbidity IndexKaplan-Meier analysisEvidence-based guidelinesThromboembolism prophylaxisVTE prophylaxisComorbidity indexKidney injuryTHA patientsFactor replacementRetrospective study
2021
Patients With Ehlers-Danlos Syndromes Experience Higher Rates of Prosthetic Dislocation After Total Hip Arthroplasty and Worse Implant Survival at 5 Years
Moore HG, Burroughs PJ, Rubin LE, Frumberg DB, Sculco PK, Grauer JN. Patients With Ehlers-Danlos Syndromes Experience Higher Rates of Prosthetic Dislocation After Total Hip Arthroplasty and Worse Implant Survival at 5 Years. Journal Of The American Academy Of Orthopaedic Surgeons 2021, 30: 177-183. PMID: 34967762, DOI: 10.5435/jaaos-d-21-00347.Peer-Reviewed Original ResearchConceptsEhlers-Danlos syndromeTotal hip arthroplastyImplant survivalHip arthroplastyAdverse eventsDiagnosis of EDSGenetic connective tissue disorderNinety-day incidenceWorse implant survivalHigh rateDay of surgeryLong-term outcomesLog-rank testMultivariate logistic regressionConnective tissue disordersMultiple organ systemsConnective tissue laxityPerioperative dislocationPeriprosthetic dislocationPostoperative complicationsPostoperative periodProsthetic dislocationHospital readmissionControl subjectsAdministrative databasesTotal Joint Arthroplasty in Patients With Achondroplasia: Comparison of 90-Day Adverse Events and 5-Year Implant Survival
Moore HG, Schneble CA, Kahan JB, Polkowski GG, Rubin LE, Grauer JN. Total Joint Arthroplasty in Patients With Achondroplasia: Comparison of 90-Day Adverse Events and 5-Year Implant Survival. Arthroplasty Today 2021, 11: 151-156. PMID: 34584919, PMCID: PMC8452593, DOI: 10.1016/j.artd.2021.08.011.Peer-Reviewed Original ResearchTotal joint arthroplastyAdverse eventsImplant survivalJoint arthroplastyFive-year implant survivalShort-term adverse eventsPrimary total hipSurgical site infectionLong-term implant successMultivariate logistic regressionTotal knee arthroplastyCommon skeletal dysplasiaMedical comorbiditiesSite infectionTotal hipPatient populationKnee arthroplastyAdministrative databasesHigher oddsLarge cohortGreater oddsPatientsImplant successSurvival curvesArthroplastyTotal Hip Arthroplasty in Patients With Cerebral Palsy: A Matched Comparison of 90-Day Adverse Events and 5-Year Implant Survival
Moore HG, Gardezi M, Burroughs PJ, Rubin LE, Frumberg DB, Grauer JN. Total Hip Arthroplasty in Patients With Cerebral Palsy: A Matched Comparison of 90-Day Adverse Events and 5-Year Implant Survival. The Journal Of Arthroplasty 2021, 36: 3534-3537. PMID: 34176692, DOI: 10.1016/j.arth.2021.05.039.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyFive-year implant survivalUrinary tract infectionCerebral palsyImplant survivalAdverse eventsTract infectionsComorbid factorsPeriprosthetic fracturesHigher oddsHip arthroplastyPerioperative urinary tract infectionNinety-day incidencePerioperative adverse eventsLong-term outcomesLog-rank testKaplan-Meier plotsMultivariate logistic regressionPerioperative complicationsPostoperative complicationsCP cohortHospital readmissionMatched ComparisonAdministrative databasesPatients