Featured Publications
The Association of Frailty With Post-ICU Disability, Nursing Home Admission, and Mortality A Longitudinal Study
Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM. The Association of Frailty With Post-ICU Disability, Nursing Home Admission, and Mortality A Longitudinal Study. CHEST Journal 2018, 153: 1378-1386. PMID: 29559308, PMCID: PMC6026287, DOI: 10.1016/j.chest.2018.03.007.Peer-Reviewed Original ResearchConceptsNursing home admissionPost-ICU disabilityHome admissionCritical illnessFrailty statusGreater disabilityNew nursing home admissionsAssociation of frailtyLikelihood of deathOne-point increaseICU admissionICU survivorsICU outcomesMean agePrognostic informationPrefrailtyFried indexAdmissionFrailtyOlder personsParent cohortAnalytic sampleFunctional activityNonfrailtyDisabilityPre–Intensive Care Unit Cognitive Status, Subsequent Disability, and New Nursing Home Admission among Critically Ill Older Adults
Ferrante LE, Murphy TE, Gahbauer EA, Leo-Summers LS, Pisani MA, Gill TM. Pre–Intensive Care Unit Cognitive Status, Subsequent Disability, and New Nursing Home Admission among Critically Ill Older Adults. Annals Of The American Thoracic Society 2018, 15: 622-629. PMID: 29446993, PMCID: PMC5949607, DOI: 10.1513/annalsats.201709-702oc.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionNew nursing home admissionsNursing home admissionCare unit admissionHome admissionCritical illnessUnit admissionModerate impairmentCognitive statusCognitive impairmentOlder adultsMinimal impairmentMultivariable analysisIntensive care unit stayMini-Mental State ExaminationProspective cohort studyIll Older AdultsModerate cognitive impairmentUnit stayCohort studySecondary outcomesSubsequent disabilityPrimary outcomeMean agePrognostic informationFunctional Trajectories Among Older Persons Before and After Critical Illness
Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM. Functional Trajectories Among Older Persons Before and After Critical Illness. JAMA Internal Medicine 2015, 175: 523-529. PMID: 25665067, PMCID: PMC4467795, DOI: 10.1001/jamainternmed.2014.7889.Peer-Reviewed Original ResearchConceptsIntensive care unitLong-term mortalityCritical illnessICU admissionModerate disabilityOlder personsMinimal disabilitySevere disabilityFunctional trajectoriesFunctional declineEarly deathProspective cohort studyDay of admissionPersons 70 yearsGoals of careRisk of deathShort-term mortalityGreater New HavenSignificant functional declineICU lengthCohort studyHospital dischargePremorbid disabilityCare unitMechanical ventilation
2020
A Clinic Blueprint for Post-Coronavirus Disease 2019 RECOVERY Learning From the Past, Looking to the Future
Lutchmansingh DD, Knauert MP, Antin-Ozerkis DE, Chupp G, Cohn L, Dela Cruz CS, Ferrante LE, Herzog EL, Koff J, Rochester CL, Ryu C, Singh I, Tickoo M, Winks V, Gulati M, Possick JD. A Clinic Blueprint for Post-Coronavirus Disease 2019 RECOVERY Learning From the Past, Looking to the Future. CHEST Journal 2020, 159: 949-958. PMID: 33159907, PMCID: PMC7641526, DOI: 10.1016/j.chest.2020.10.067.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAcute diseaseRespiratory syndromeSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Post-intensive care syndromePotential long-term complicationsCOVID-19Respiratory syndrome coronavirus 2Middle East respiratory syndromeSevere acute respiratory syndromeCoronavirus disease 2019 (COVID-19) casesPersistent respiratory symptomsLong-term complicationsCOVID-19 survivorsSyndrome coronavirus 2Acute respiratory syndromeCOVID-19 outcomesChronic complicationsPersistent symptomsRespiratory symptomsCoronavirus 2Lung diseaseNonhospitalized individualsClinical programsComplications
2018
The Competing Risk of Death in Longitudinal Geriatric Outcomes
Murphy TE, Gill TM, Leo‐Summers L, Gahbauer EA, Pisani MA, Ferrante LE. The Competing Risk of Death in Longitudinal Geriatric Outcomes. Journal Of The American Geriatrics Society 2018, 67: 357-362. PMID: 30537050, PMCID: PMC6367003, DOI: 10.1111/jgs.15697.Peer-Reviewed Original ResearchConceptsFall-related hospitalizationsRisk of deathProspective cohort studyPersons 70 yearsLong-term followPrecipitating Events ProjectCommunity-based dataLongitudinal studyGeriatric outcomesCohort studyFried phenotypeFunctional recoveryTotal disabilityOutcome eventsDaily livingClinical scenariosSecondary analysisOlder personsVision impairmentDeathBasic activitiesOutcomesDisabilityDecedentsRisk
2015
Understanding and Reducing Disability in Older Adults Following Critical Illness*
Brummel NE, Balas MC, Morandi A, Ferrante LE, Gill TM, Ely EW. Understanding and Reducing Disability in Older Adults Following Critical Illness*. Critical Care Medicine 2015, 43: 1265-1275. PMID: 25756418, PMCID: PMC4640688, DOI: 10.1097/ccm.0000000000000924.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCritical illnessOlder adultsDisability outcomesDaily livingAcute critical illnessCognitive outcomesModifiable risk factorsGeriatric care modelsLong-term disabilitySevere cognitive impairmentWeb of ScienceIll patientsGeriatric conditionsPoor outcomeHeavy sedationIncident dementiaICU practiceRisk factorsEpidemiologic dataInstrumental activitiesCare modelCognitive declineCognitive impairmentIllnessAdditional citations