Anti-Inflammatory Effects of Levalbuterol-Induced 11β-Hydroxysteroid Dehydrogenase Type 1 Activity in Airway Epithelial Cells
Randall MJ, Kostin SF, Burgess EJ, Hoyt LR, Ather JL, Lundblad LK, Poynter ME. Anti-Inflammatory Effects of Levalbuterol-Induced 11β-Hydroxysteroid Dehydrogenase Type 1 Activity in Airway Epithelial Cells. Frontiers In Endocrinology 2015, 5: 236. PMID: 25628603, PMCID: PMC4290686, DOI: 10.3389/fendo.2014.00236.Peer-Reviewed Original ResearchAirway epithelial cellsPro-inflammatory cytokine productionNF-κB activationAsthmatic subjectsCytokine productionRacemic albuterolEpithelial cellsEpithelial NF-κB activationAnti-inflammatory effectsNF-κB transcriptional activityTumor necrosis factorType 1 activityNF-κB activityAirway inflammationAllergic asthmaEndogenous glucocorticoidsLung functionCombination therapyNecrosis factorCorticosteroidsLuc activityAugments expressionAlbuterolMouse modelNF-κB