2013
Reproducibility of research and preclinical validation: problems and solutions
Pusztai L, Hatzis C, Andre F. Reproducibility of research and preclinical validation: problems and solutions. Nature Reviews Clinical Oncology 2013, 10: 720-724. PMID: 24080600, DOI: 10.1038/nrclinonc.2013.171.Peer-Reviewed Original Research
2011
Challenges translating breast cancer gene signatures into the clinic
Weigelt B, Pusztai L, Ashworth A, Reis-Filho JS. Challenges translating breast cancer gene signatures into the clinic. Nature Reviews Clinical Oncology 2011, 9: 58-64. PMID: 21878891, DOI: 10.1038/nrclinonc.2011.125.Peer-Reviewed Original Research
2008
Advances in translational research in breast cancer; a bridge to future therapies
Sotiriou C, Pusztai L. Advances in translational research in breast cancer; a bridge to future therapies. European Journal Of Cancer 2008, 44: 2705-2706. PMID: 19028087, DOI: 10.1016/j.ejca.2008.10.007.Peer-Reviewed Original ResearchResearch Issues Affecting Preoperative Systemic Therapy for Operable Breast Cancer
Wolff AC, Berry D, Carey LA, Colleoni M, Dowsett M, Ellis M, Garber JE, Mankoff D, Paik S, Pusztai L, Smith ML, Zujewski J. Research Issues Affecting Preoperative Systemic Therapy for Operable Breast Cancer. Journal Of Clinical Oncology 2008, 26: 806-813. PMID: 18258990, DOI: 10.1200/jco.2007.15.2983.Peer-Reviewed Original ResearchMeSH KeywordsAngiogenesis InhibitorsAntineoplastic AgentsApoptosisBiomarkersBiomedical ResearchBreast NeoplasmsCell ProliferationEpidemiologic Research DesignErbB ReceptorsEthics, ClinicalFemaleGene Expression ProfilingHumansMastectomy, SegmentalNeoadjuvant TherapyPatient AdvocacyPreoperative CarePrognosisReceptors, SteroidTreatment OutcomeConceptsPreoperative systemic therapyOperable breast cancerSystemic therapyBreast cancerTrial designEnd pointCohesive multidisciplinary teamBreast conservation ratesEffective alternative therapyTrial end pointsLong-term outcomesSpecific breast cancer subtypesPredictors of responseNovel trial designsIntermediate end pointsBreast cancer subtypesIndividual patient subgroupsAdjuvant trialsPatient subgroupsSmall trialsAlternative therapiesMAIN OUTCOMEClinical careCancer subtypesMultidisciplinary team
2006
Chips to Bedside: Incorporation of Microarray Data into Clinical Practice
Pusztai L. Chips to Bedside: Incorporation of Microarray Data into Clinical Practice. Clinical Cancer Research 2006, 12: 7209-7214. PMID: 17189391, DOI: 10.1158/1078-0432.ccr-06-2649.Peer-Reviewed Original Research