2010
Stability of estrogen receptor status in breast carcinoma
Gong Y, Han EY, Guo M, Pusztai L, Sneige N. Stability of estrogen receptor status in breast carcinoma. Cancer 2010, 117: 705-713. PMID: 20939012, DOI: 10.1002/cncr.25506.Peer-Reviewed Original ResearchConceptsER statusBreast carcinomaEndocrine therapyMetastatic sitesPrimary tumorMetastatic tumorsMetastatic breast carcinomaEstrogen receptor statusER discordanceDisease courseReceptor statusSystemic therapyClinical courseER expressionER testingClinical managementNegative conversionER assaysDiscordant casesCarcinomaPositive conversionTumorsPatientsMetastasisTherapy
2009
Prognostic impact of discordance between triple-receptor measurements in primary and recurrent breast cancer
Liedtke C, Broglio K, Moulder S, Hsu L, Kau S, Symmans WF, Albarracin C, Meric-Bernstam F, Woodward W, Theriault RL, Kiesel L, Hortobagyi GN, Pusztai L, Gonzalez-Angulo AM. Prognostic impact of discordance between triple-receptor measurements in primary and recurrent breast cancer. Annals Of Oncology 2009, 20: 1953-1958. PMID: 19596702, PMCID: PMC2791352, DOI: 10.1093/annonc/mdp263.Peer-Reviewed Original ResearchConceptsTriple receptor-negative breast cancerRecurrent breast cancerPost-recurrence survivalProgesterone receptorRecurrent tumorsBreast cancerEstrogen receptorDiscordant casesBetter post-recurrence survivalReceptor-positive breast cancerReceptor-negative breast cancerDiscordant receptor statusHormone receptor measurementsPrognostic impactReceptor statusUnfavorable survivalPathological parametersHER2 statusPoor survivalReceptor measurementsIHC scorePatientsClinical phenotypeSuboptimal reproducibilityCancer