2023
Within-city spatial variations in long-term average outdoor oxidant gas concentrations and cardiovascular mortality: Effect modification by oxidative potential in the Canadian Census Health and Environment Cohort
Ripley S, Gao D, Pollitt K, Lakey P, Shiraiwa M, Hatzopoulou M, Weichenthal S. Within-city spatial variations in long-term average outdoor oxidant gas concentrations and cardiovascular mortality: Effect modification by oxidative potential in the Canadian Census Health and Environment Cohort. Environmental Epidemiology 2023, 7: e257. PMID: 37545813, PMCID: PMC10403014, DOI: 10.1097/ee9.0000000000000257.Peer-Reviewed Original ResearchCanadian Census HealthCardiovascular mortalityReactive oxygen species concentrationParticulate air pollutionEnvironment CohortMeasures of PMRetrospective cohort studyFine particulate air pollutionRelevant confounding factorsProportional hazards modelOutdoor fine particulate air pollutionPopulation health impactHealth impactsCardiovascular health impactsOutdoor air pollutionCardiovascular deathCohort studyOxidant gasesEffect modificationHazards modelConfounding factorsMortalityOxidative stressHealth effectsOxidative potential
2022
Air Pollution and Pediatric Respiratory Hospitalizations: Effect Modification by Particle Constituents and Oxidative Potential.
Korsiak J, Lavigne E, You H, Pollitt K, Kulka R, Hatzopoulou M, Evans G, Burnett RT, Weichenthal S. Air Pollution and Pediatric Respiratory Hospitalizations: Effect Modification by Particle Constituents and Oxidative Potential. American Journal Of Respiratory And Critical Care Medicine 2022, 206: 1370-1378. PMID: 35802828, DOI: 10.1164/rccm.202205-0896oc.Peer-Reviewed Original ResearchConceptsRespiratory hospitalizationsConditional logistic regression modelsPediatric respiratory hospitalizationsFine particulate air pollutionCase-crossover studyLogistic regression modelsParticulate air pollutionOxidant gasesRespiratory healthEffect modificationOdds ratioHospitalizationParticle oxidative potentialStrong associationConfidence intervalsOxidative potentialMedianPositive associationChildrenAssociationMedian valueRegression modelsFine particulate matterOutdoor fine particlesAir pollutionLong-term Exposure to Oxidant Gases and Mortality: Effect Modification by PM2.5 Transition Metals and Oxidative Potential
Toyib O, Lavigne E, Traub A, Umbrio D, You H, Ripley S, Pollitt K, Shin T, Kulka R, Jessiman B, Tjepkema M, Martin R, Stieb DM, Hatzopoulou M, Evans G, Burnett RT, Weichenthal S. Long-term Exposure to Oxidant Gases and Mortality: Effect Modification by PM2.5 Transition Metals and Oxidative Potential. Epidemiology 2022, 33: 767-776. PMID: 36165987, PMCID: PMC9531968, DOI: 10.1097/ede.0000000000001538.Peer-Reviewed Original ResearchConceptsLong-term exposureOxidative stressFine particulate air pollutionProportional hazards modelAir pollution health effectsHealth impactsObserved health impactsParticulate air pollutionCohort studyMortality outcomesOxidant gasesEffect modificationInterquartile increaseHazards modelAdverse health impactsNonaccidental mortalityGSH levelsHealth effectsMortalityLand use regression modelsOxidative potentialMedianRegression modelsExposurePM 2.5Associations between short-term ambient PM2.5, oxidant gases and respiratory hospitalizations in children: effect modification by PM2.5 transition metals, sulfur and oxidative potential
Korsiak J, Lavigne E, You H, Pollitt K, Kulka R, Hatzopoulou M, Evans G, Burnett R, Weichenthal S. Associations between short-term ambient PM2.5, oxidant gases and respiratory hospitalizations in children: effect modification by PM2.5 transition metals, sulfur and oxidative potential. ISEE Conference Abstracts 2022, 2022 DOI: 10.1289/isee.2022.o-pk-01.Peer-Reviewed Original Research
2018
Fine Particulate Air Pollution and Adverse Birth Outcomes: Effect Modification by Regional Nonvolatile Oxidative Potential
Lavigne É, Burnett RT, Stieb DM, Evans GJ, Godri Pollitt KJ, Chen H, van Rijswijk D, Weichenthal S. Fine Particulate Air Pollution and Adverse Birth Outcomes: Effect Modification by Regional Nonvolatile Oxidative Potential. Environmental Health Perspectives 2018, 126: 077012. PMID: 30073952, PMCID: PMC6108848, DOI: 10.1289/ehp2535.Peer-Reviewed Original ResearchConceptsTerm low birth weightLow birth weightAdverse birth outcomesPreterm birthBirth outcomesHighest quartileBirth weightEffect modificationFirst trimester PMRetrospective cohort studyTerm birth weightFine particulate air pollutionPossible effect modificationDays of deliveryFine particulate matter air pollutionParticulate matter air pollutionMatter air pollutionEffects of PMEstimate of effectParticulate air pollutionPreterm deliveryCohort studySingleton birthsPrenatal exposureImpact of PM
2016
Fine Particulate Matter and Emergency Room Visits for Respiratory Illness. Effect Modification by Oxidative Potential
Weichenthal SA, Lavigne E, Evans GJ, Pollitt K, Burnett RT. Fine Particulate Matter and Emergency Room Visits for Respiratory Illness. Effect Modification by Oxidative Potential. American Journal Of Respiratory And Critical Care Medicine 2016, 194: 577-86. PMID: 26963193, DOI: 10.1164/rccm.201512-2434oc.Peer-Reviewed Original ResearchConceptsEmergency room visitsAcute respiratory morbidityRespiratory illnessRoom visitsImpact of PM2.5Respiratory morbidityChronic obstructive pulmonary diseaseAcute respiratory illnessObstructive pulmonary diseaseFine particulate air pollutionCases of asthmaConditional logistic regressionCase-crossover studyParticulate air pollutionRespiratory outcomesPulmonary diseaseEmergency roomEffect modificationRespiratory tractDaily air pollution dataInterquartile changeTime-varying covariatesOxidative burdenIllnessLogistic regressionFine particulate air pollution and adverse birth outcomes: Effect modification by oxidative potential
Lavigne* E, Weichenthal S, Evans G, Godri-Pollitt K, Chen H, Burnett R. Fine particulate air pollution and adverse birth outcomes: Effect modification by oxidative potential. ISEE Conference Abstracts 2016, 2016 DOI: 10.1289/isee.2016.4633.Peer-Reviewed Original Research