New considerations for hiPSC-based models of neuropsychiatric disorders
Hoffman GE, Schrode N, Flaherty E, Brennand KJ. New considerations for hiPSC-based models of neuropsychiatric disorders. Molecular Psychiatry 2018, 24: 49-66. PMID: 29483625, PMCID: PMC6109625, DOI: 10.1038/s41380-018-0029-1.Peer-Reviewed Original ResearchConceptsHuman-induced pluripotent stem cellsCell type compositionComplex genetic diseasesPluripotent stem cellsComplex genetic disorderField of geneticsCell biologistsBiological convergenceLevel phenotypesAdvanced geneticsCRISPR technologyHuman diseasesPsychiatric genomicsGenetic diseasesStem cellsNeural cellsCommon variantsGeneticsGenetic disordersBiological considerationsCritical insightsCellsGenomicsRecent advancesBiologists