2005
Half-a-dozen ribs: The breakpoint for mortality
Flagel BT, Luchette FA, Reed RL, Esposito TJ, Davis KA, Santaniello JM, Gamelli RL. Half-a-dozen ribs: The breakpoint for mortality. Surgery 2005, 138: 717-725. PMID: 16269301, DOI: 10.1016/j.surg.2005.07.022.Peer-Reviewed Original ResearchConceptsAcute respiratory distress syndromeInjury Severity ScoreEpidural analgesiaRespiratory distress syndromeHospital LOSRib fracturesMortality rateICU LOSPulmonary morbidityAspiration pneumoniaDistress syndromeMechanical ventilationSeverity scoreIntensive care unit lengthNational Trauma Data BankMore fractured ribsMore rib fracturesOccurrence of pneumoniaOverall mortality rateChest wall injuryModalities of treatmentDiseases-9 codesTrauma Data BankStudent's t-testPulmonary complications
2004
Burn Injury and Pulmonary Sepsis: Development of a Clinically Relevant Model
Davis KA, Santaniello JM, He LK, Muthu K, Sen S, Jones SB, Gamelli RL, Shankar R. Burn Injury and Pulmonary Sepsis: Development of a Clinically Relevant Model. Journal Of Trauma And Acute Care Surgery 2004, 56: 272-278. PMID: 14960967, DOI: 10.1097/01.ta.0000108995.64133.90.Peer-Reviewed Original ResearchConceptsColony-stimulating factorPulmonary sepsisCytokine tumor necrosisSystemic sepsisInterleukin-6Tumor necrosisProinflammatory cytokine tumor necrosisInflammatory cytokine tumor necrosisAlveolar macrophage releaseBurn/traumaDorsal scald burnGram stainMultiple organ failureDevelopment of pneumoniaGranulocyte-macrophage (GM) CSFFemoral bone marrow cellsEnd-organ responseIsolated alveolar macrophagesPositive tissue culturesPseudomonas aeruginosaWhole lung tissueMale B6D2F1 miceTissue Gram stainMacrophage colony-stimulating factorBone marrow cells