2021
Cerebral Microbleeds and Acute Hematoma Characteristics in the ATACH-2 and MISTIE III Trials
Magid-Bernstein JR, Li Y, Cho SM, Piran PJ, Roh DJ, Gupta A, Shoamanesh A, Merkler A, Zhang C, Avadhani R, Montano N, Iadecola C, Falcone G, Sheth K, Qureshi AI, Rosand J, Goldstein J, Awad I, Hanley D, Kamel H, Ziai WC, Murthy SB. Cerebral Microbleeds and Acute Hematoma Characteristics in the ATACH-2 and MISTIE III Trials. Neurology 2021, 98: e1013-e1020. PMID: 34937780, PMCID: PMC8967392, DOI: 10.1212/wnl.0000000000013247.Peer-Reviewed Original ResearchConceptsSmaller ICH volumeCerebral microbleedsSmall vessel diseaseIntracerebral hemorrhageHematoma expansionHematoma characteristicsICH volumeVessel diseaseNumber of CMBsSmaller baseline hematoma volumesUnderlying small vessel diseasePresence of CMBsCerebral small vessel diseaseAdmission ICH volumeMISTIE III trialPresence of microbleedsClass II evidencePhase 3 trialSeverity of leukoaraiosisPrimary intracerebral hemorrhageBaseline hematoma volumeIndividual patient dataBrain MRI scansLogistic regression modelsAntihypertensive treatment
2017
Intracerebral Hemorrhage
Stevenson D, Sheth K. Intracerebral Hemorrhage. 2017, 75-91. DOI: 10.1007/978-3-319-48669-7_5.Peer-Reviewed Original ResearchSecondary intracerebral hemorrhageIntracerebral hemorrhageNontraumatic intracerebral hemorrhageIschemic strokeChronic small vessel diseasePrimary intracerebral hemorrhageSmall vessel diseaseCritical care settingHemorrhagic transformationCerebral edemaBlood pressureThorough historyBlood glucoseBrain parenchymaPhysical examVascular malformationsDistinct pathophysiologyIntracranial pressureAnatomical anomaliesCare settingsHemorrhageStrokeFinal manifestationEdemaPatients