2004
Megakaryoblastic Leukemia Factor-1 Transduces Cytoskeletal Signals and Induces Smooth Muscle Cell Differentiation from Undifferentiated Embryonic Stem Cells*
Du KL, Chen M, Li J, Lepore JJ, Mericko P, Parmacek MS. Megakaryoblastic Leukemia Factor-1 Transduces Cytoskeletal Signals and Induces Smooth Muscle Cell Differentiation from Undifferentiated Embryonic Stem Cells*. Journal Of Biological Chemistry 2004, 279: 17578-17586. PMID: 14970199, DOI: 10.1074/jbc.m400961200.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlotting, NorthernCell DifferentiationCell NucleusCells, CulturedChromatinCOS CellsCytoplasmCytoskeletonDNA-Binding ProteinsDNA, ComplementaryEmbryo, MammalianGenes, DominantHumansImmunohistochemistryLuciferasesMiceMyocytes, Smooth MuscleNIH 3T3 CellsNuclear ProteinsOncogene Proteins, FusionPlasmidsPrecipitin TestsPromoter Regions, GeneticProtein BindingProtein Structure, TertiaryProtein TransportReverse Transcriptase Polymerase Chain ReactionSignal TransductionStem CellsTissue DistributionTrans-ActivatorsTranscriptional ActivationTransfectionTwo-Hybrid System TechniquesConceptsSmooth muscle cell differentiationMuscle cell differentiationEmbryonic stem cellsPromoter/enhancerSmooth muscle cellsRhoA signalingSM22alpha promoterCell differentiationUndifferentiated embryonic stem cellsSerum response factorTranscription factor myocardinLeucine zipper domainTranscriptional regulatory elementsStem cellsMost human tissuesCytoskeletal signalsTranscriptional programsTransduce signalsMKL1 mutantSMC differentiationZipper domainRegulatory elementsActin polymerizationMKL1 geneSerum stimulation
2002
SM22β encodes a lineage-restricted cytoskeletal protein with a unique developmentally regulated pattern of expression
Zhang JC, Helmke BP, Shum A, Du K, Yu WW, Lu MM, Davies PF, Parmacek MS. SM22β encodes a lineage-restricted cytoskeletal protein with a unique developmentally regulated pattern of expression. Cells And Development 2002, 115: 161-166. PMID: 12049783, DOI: 10.1016/s0925-4773(02)00088-6.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAmino Acid SequenceAnimalsBase SequenceCell LineageCells, CulturedCytoskeletal ProteinsDNA, ComplementaryGene Expression ProfilingGene Expression Regulation, DevelopmentalHumansMiceMolecular Sequence DataMuscle ProteinsMuscle, Smooth, VascularRatsSubcellular FractionsTissue DistributionConceptsCytoskeletal proteinsRegulated patternLineage-restricted patternsMouse embryonic developmentMuscle-specific proteinsCytoskeletal actin filamentsRegulated genesNovel actinNeuron-specific proteinRepeat domainEmbryonic developmentAcid polypeptideSequence identitySpecific proteinsActin filamentsIntracellular signalingLung mesenchymeGastrointestinal epithelial cellsSM22alphaCartilaginous primordiaProteinCellular morphologySmooth muscle cellsEpithelial cellsMuscle cells