2022
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding
Li D, Ong S, Hughes M, Hung K, Agarwal R, Alexis J, Damianos J, Sharma S, Pires J, Nanna M, Laine L. Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding. Alimentary Pharmacology & Therapeutics 2022, 57: 94-102. PMID: 36394111, DOI: 10.1111/apt.17278.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsGastrointestinal bleedingPrimary preventionCardiovascular eventsRisk of MACEYale-New Haven HospitalPrimary cardiovascular preventionAdverse cardiovascular eventsKaplan-Meier curvesLong-term outcomesRisk-benefit ratioLog-rank testAspirin 81Hospitalised patientsPrimary endpointSecondary endpointsCardiovascular preventionSubsequent hospitalisationMedian ageDeprescriptionHigh riskAspirinHospitalisationPatientsPrevention
2019
Factors Associated With Adherence to Helicobacter pylori Testing During Hospitalization for Bleeding Peptic Ulcer Disease
Hung KW, Knotts RM, Faye AS, Pont AR, Lebwohl B, Abrams JA, Freedberg DE. Factors Associated With Adherence to Helicobacter pylori Testing During Hospitalization for Bleeding Peptic Ulcer Disease. Clinical Gastroenterology And Hepatology 2019, 18: 1091-1098.e1. PMID: 31352090, DOI: 10.1016/j.cgh.2019.07.037.Peer-Reviewed Original ResearchConceptsPeptic ulcer diseaseIntensive care unitH pyloriUlcer diseaseGastrointestinal bleedingDuodenal ulcerPylori infectionKaplan-Meier analysisH pylori infectionHelicobacter pylori infectionYear of admissionHelicobacter pylori testingElectronic medical recordsEvidence of testsIndex endoscopyCoagulation statusComposite outcomeEndoscopic factorsBlood lossHospital admissionCare unitRetrospective studyMedical recordsMultivariable modelUlcer severity