Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative Outcome
Pawlik TM, Olino K, Gleisner AL, Torbenson M, Schulick R, Choti MA. Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative Outcome. Journal Of Gastrointestinal Surgery 2007, 11: 860-868. PMID: 17492335, DOI: 10.1007/s11605-007-0149-4.Peer-Reviewed Original ResearchConceptsColorectal liver metastasesPreoperative chemotherapyHepatic colorectal metastasesHepatic injuryChemotherapy groupColorectal metastasesHepatic resectionLiver metastasesFluoropyrimidine-based regimensPerioperative complication rateMajority of patientsChemotherapy detailsEligible patientsChemotherapy regimenPerioperative morbidityComplication ratePostoperative outcomesClinicopathologic characteristicsLiver injurySinusoidal dilatationHepatic histologyNontumorous liverSuch injuriesChemotherapyPatients