2017
A Comparison of Methods for Estimating the Determinant of High-Dimensional Covariance Matrix
Hu Z, Dong K, Dai W, Tong T. A Comparison of Methods for Estimating the Determinant of High-Dimensional Covariance Matrix. The International Journal Of Biostatistics 2017, 13: 20170013. PMID: 28953454, DOI: 10.1515/ijb-2017-0013.Peer-Reviewed Original ResearchConceptsHigh-dimensional covariance matricesCovariance matrixCovariance matrix estimationMatrix estimation methodExtensive simulation studyHigh-dimensional dataStatistical inferenceCovariance matrix estimation methodMatrix estimationComputational challengesInformation theoryEstimation methodSimulation studyHigh dimensionalityLoss functionStatistical testsComparison resultsReal applicationsInteresting comparison resultsComparison of methodsMatrixRecent proposalSample sizeDimensionalityTheory
2016
NBLDA: negative binomial linear discriminant analysis for RNA-Seq data
Dong K, Zhao H, Tong T, Wan X. NBLDA: negative binomial linear discriminant analysis for RNA-Seq data. BMC Bioinformatics 2016, 17: 369. PMID: 27623864, PMCID: PMC5022247, DOI: 10.1186/s12859-016-1208-1.Peer-Reviewed Original ResearchConceptsNegative binomial linear discriminant analysisNegative binomial distributionNegative binomial variablesPresence of overdispersionBinomial distributionSimulation resultsUnknown parametersNegative binomial modelBinomial modelReal RNA-seq data setsRNA-seq data classificationStatistical methodsDispersion parametersCount dataR codePoisson assumptionLinear discriminant analysisReal-world applicationsPoisson distributionImpact of dispersionDiscrete natureBinomial variablesComparison resultsBinomial classifierWitten