1992
Adhesion of a chicken myeloblast cell line to fibrinogen and vitronectin through a beta 1-class integrin.
Neugebauer K, Venstrom K, Reichardt L. Adhesion of a chicken myeloblast cell line to fibrinogen and vitronectin through a beta 1-class integrin. Journal Of Cell Biology 1992, 116: 809-815. PMID: 1370500, PMCID: PMC2289312, DOI: 10.1083/jcb.116.3.809.Peer-Reviewed Original ResearchConceptsMyeloblast cell lineHD11 cellsCell adhesionCell linesExtracellular matrix ligandsExtracellular matrix proteinsAlpha v beta 3Function-perturbing antibodiesAdhesive interactionsExtracellular matrix constituentsSubunit associatesHD11 cell lineReceptor-mediated eventsMatrix ligandsBeta subunitIntegrin heterodimersMatrix proteinsFunction-blocking antibodiesAlpha vLipopolysaccharide treatmentPrimary macrophagesHeterodimersDistinct extracellular matrix (ECM) proteinsBeta 3Study of mechanismsAdhesive interactions that regulate development of the retina and primary visual projection.
Reichardt L, Bossy B, de Curtis I, Neugebauer K, Venstrom K, Sretavan D. Adhesive interactions that regulate development of the retina and primary visual projection. Cold Spring Harbor Symposia On Quantitative Biology 1992, 57: 419-29. PMID: 1339677, DOI: 10.1101/sqb.1992.057.01.047.Peer-Reviewed Original Research
1991
Cell-surface regulation of β1-integrin activity on developing retinal neurons
Neugebauer K, Rekhardt L. Cell-surface regulation of β1-integrin activity on developing retinal neurons. Nature 1991, 350: 68-71. PMID: 1706071, PMCID: PMC2710139, DOI: 10.1038/350068a0.Peer-Reviewed Original ResearchVitronectin and thrombospondin promote retinal neurite outgrowth: Developmental regulation and role of integrins
Neugebauer K, Emmett C, Venstrom K, Reichardt L. Vitronectin and thrombospondin promote retinal neurite outgrowth: Developmental regulation and role of integrins. Neuron 1991, 6: 345-358. PMID: 1705807, DOI: 10.1016/0896-6273(91)90244-t.Peer-Reviewed Original ResearchConceptsRetinal neuronsEmbryonic chick retinal neuronsChick retinal neuronsNeurite outgrowthNeurite outgrowth-promoting moleculesRetinal neurite outgrowthBeta 1 subunitRole of integrinsAxonal growthAlpha vSpecific receptorsRetinal developmentNeuronal developmentExtracellular matrix glycoproteinNeuronsReceptorsNeuroretinaThrombospondinMatrix glycoproteinGlycoproteinVitronectin
1990
Neuronal receptors that regulate axon growth.
Reichardt L, Bossy B, Carbonetto S, de Curtis I, Emmett C, Hall D, Ignatius M, Lefcort F, Napolitano E, Large T, Neugebauer K, Tomaselli K. Neuronal receptors that regulate axon growth. Cold Spring Harbor Symposia On Quantitative Biology 1990, 55: 341-50. PMID: 2132826, DOI: 10.1101/sqb.1990.055.01.035.Peer-Reviewed Original Research
1989
Integrins and Cell Adhesion Molecules: Neuronal Receptors That Regulate Axon Growth on Extracellular Matrices and Cell Surfaces
Reichardt L, Bixby J, Hall D, Ignatius M, Neugebauer K, Tomaselli K. Integrins and Cell Adhesion Molecules: Neuronal Receptors That Regulate Axon Growth on Extracellular Matrices and Cell Surfaces. Developmental Neuroscience 1989, 11: 332-347. PMID: 2551626, DOI: 10.1159/000111910.Peer-Reviewed Original Research
1988
N-cadherin, NCAM, and integrins promote retinal neurite outgrowth on astrocytes in vitro.
Neugebauer K, Tomaselli K, Lilien J, Reichardt L. N-cadherin, NCAM, and integrins promote retinal neurite outgrowth on astrocytes in vitro. Journal Of Cell Biology 1988, 107: 1177-1187. PMID: 3262111, PMCID: PMC2115273, DOI: 10.1083/jcb.107.3.1177.Peer-Reviewed Original ResearchConceptsRetinal neuronsRetinal neurite outgrowthOptic pathwayCell adhesion moleculeNeurite outgrowthAdhesion moleculesEmbryonic chick retinal neuronsInhibitory effectRetinal ganglion neuronsChick retinal neuronsNeuronal cell surface proteinsN-cadherinDetectable inhibitory effectAttachment of neuronsEmbryonic day 7Ganglion neuronsDay 7Astrocyte monolayersIntegrin extracellular matrix receptorsNeuronsCell surface proteinsExtracellular matrix receptorsNCAMAstrocytesAxon extensionN-cadherin and integrins: Two receptor systems that mediate neuronal process outgrowth on astrocyte surfaces
Tomaselli K, Neugebauer K, Bixby J, Lilien J, Reichard L. N-cadherin and integrins: Two receptor systems that mediate neuronal process outgrowth on astrocyte surfaces. Neuron 1988, 1: 33-43. PMID: 2856086, DOI: 10.1016/0896-6273(88)90207-3.Peer-Reviewed Original ResearchConceptsBeta 1 antibodyCultured astrocytesNeurite outgrowthN-cadherinReceptor systemProcess outgrowthCiliary ganglion neuronsNeuronal cell surface proteinsLack of effectReceptor-mediated interactionsNeuronal process outgrowthGanglion neuronsCell adhesion moleculeAstrocyte surfaceCNS axonsNeuronal receptorsAstrocytesOutgrowth of neuritesAxon growthAdhesion moleculesNeuronsN-CAMAntibodiesReceptor heterodimersCell surface proteins
1987
Embryonic neural retinal cell response to extracellular matrix proteins: developmental changes and effects of the cell substratum attachment antibody (CSAT).
Hall D, Neugebauer K, Reichardt L. Embryonic neural retinal cell response to extracellular matrix proteins: developmental changes and effects of the cell substratum attachment antibody (CSAT). Journal Of Cell Biology 1987, 104: 623-634. PMID: 3493247, PMCID: PMC2114555, DOI: 10.1083/jcb.104.3.623.Peer-Reviewed Original ResearchConceptsCSAT antibodySubstrate preferenceNeurite outgrowthNeural retinal cellsExtracellular matrix substratesProfile of proteinsExtracellular matrix proteinsCollagen IVExtracellular matrix constituentsCell surface glycoproteinExtracellular matrix glycoproteinCell attachmentCell surface moleculesRetinal cellsCellular responsesMatrix proteinsNeuronal differentiationMatrix substratesEmbryonic day 6Matrix glycoproteinNeurite extensionProteinSurface glycoproteinCell interactionsSurface molecules