Deficient serum 25-hydroxyvitamin D is associated with an atherogenic lipid profile: The Very Large Database of Lipids (VLDL-3) study
Lupton JR, Faridi KF, Martin SS, Sharma S, Kulkarni K, Jones SR, Michos ED. Deficient serum 25-hydroxyvitamin D is associated with an atherogenic lipid profile: The Very Large Database of Lipids (VLDL-3) study. Journal Of Clinical Lipidology 2015, 10: 72-81.e1. PMID: 26892123, PMCID: PMC4762185, DOI: 10.1016/j.jacl.2015.09.006.Peer-Reviewed Original ResearchConceptsLow-density lipoprotein cholesterolIntermediate-density lipoprotein cholesterolAtherogenic lipid profileLipoprotein cholesterolRemnant lipoprotein cholesterolLipid profileLipid panelHigh-density lipoprotein cholesterolMultivariable-adjusted linear regressionVitamin D supplementationHigher total cholesterolSerum vitamin DCardiovascular disease riskLow serum HDLBlood urea nitrogenCross-sectional studyMultivariable linear regressionAdditional outcome measurementD supplementationGlycemic statusLow HDLHemoglobin A1cTotal cholesterolKidney functionSerum HDLRelationship of the triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio to the remainder of the lipid profile: The Very Large Database of Lipids-4 (VLDL-4) study
Quispe R, Manalac RJ, Faridi KF, Blaha MJ, Toth PP, Kulkarni KR, Nasir K, Virani SS, Banach M, Blumenthal RS, Martin SS, Jones SR. Relationship of the triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio to the remainder of the lipid profile: The Very Large Database of Lipids-4 (VLDL-4) study. Atherosclerosis 2015, 242: 243-250. PMID: 26232164, DOI: 10.1016/j.atherosclerosis.2015.06.057.Peer-Reviewed Original ResearchConceptsHigh-density lipoprotein cholesterol ratioLipoprotein cholesterol ratioLipid profileLDL densityCholesterol ratioAtherogenic lipid phenotypeLevels of RLPMedian TgMetabolic syndromeLipid parametersCohort representativeInsulin resistanceMean ageStudy populationElevated TGGeneral U.S.Higher RLPUS individualsLipid phenotypesDemographic informationHighest relative increaseTriglyceridesRLPAgeRelative increase