Synergistic effects of Cinnamomum cassia L. essential oil in combination with polymyxin B against carbapenemase-producing Klebsiella pneumoniae and Serratia marcescens
Vasconcelos N, de Sá Queiroz J, da Silva K, de Paula Vasconcelos P, Croda J, Simionatto S. Synergistic effects of Cinnamomum cassia L. essential oil in combination with polymyxin B against carbapenemase-producing Klebsiella pneumoniae and Serratia marcescens. PLOS ONE 2020, 15: e0236505. PMID: 32701970, PMCID: PMC7377461, DOI: 10.1371/journal.pone.0236505.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBacterial ProteinsBeta-LactamasesCinnamomum aromaticumDrug Resistance, Multiple, BacterialDrug SynergismHumansKlebsiella InfectionsKlebsiella pneumoniaeOils, VolatilePolymyxin BSerratia InfectionsSerratia marcescensSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAntibacterial activity of Cinnamomum cassia L. essential oil in a carbapenem- and polymyxin-resistant Klebsiella aerogenes strain
Vasconcelos N, Silva K, Croda J, Simionatto S. Antibacterial activity of Cinnamomum cassia L. essential oil in a carbapenem- and polymyxin-resistant Klebsiella aerogenes strain. Revista Da Sociedade Brasileira De Medicina Tropical 2020, 53: e20200032. PMID: 33027413, PMCID: PMC7534965, DOI: 10.1590/0037-8682-0032-2020.Peer-Reviewed Original ResearchConceptsHigh antibiotic resistanceMultidrug resistance profilesTime-kill methodsBla OXA-1Multidrug-resistant bacteriaMinimum inhibitory concentrationBla TEMBla CTXAntibacterial activityInhibitory effectBroth microdilutionInhibitory concentrationAntibiotic resistanceK. aerogenesOXA-1KPC-2CarbapenemsCinnamomum cassia essential oilL. essential oilCassia essential oilEssential oilCTXActivity