Evaluation of the anti-mycobacterium tuberculosis activity and in vivo acute toxicity of Annona sylvatic
Araujo R, Neves F, Formagio A, Kassuya C, Stefanello M, Souza V, Pavan F, Croda J. Evaluation of the anti-mycobacterium tuberculosis activity and in vivo acute toxicity of Annona sylvatic. BMC Complementary Medicine And Therapies 2014, 14: 209. PMID: 24974069, PMCID: PMC4082671, DOI: 10.1186/1472-6882-14-209.Peer-Reviewed Original ResearchConceptsVivo acute toxicityAnti-mycobacterial activityLC-MSFirst chemical characterizationAnti-Mycobacterium tuberculosis activityLiquid-liquid partitioningMinimal inhibitory concentrationEthyl acetate fractionChemical characterizationAntituberculosis activitySpectroscopic dataBody weightIsolation of quercetinAcute toxicityChemical fractionationChromatographic analysisFemale Swiss miceMultidrug-resistant Mycobacterium tuberculosis strainsControl of tuberculosisAcute toxicity evaluationToxicity evaluationMycobacterium tuberculosis strainsTuberculosis activityAlmunequinEAF fractions