Characterization of Long Noncoding RNA and mRNA Profiles in Sepsis-Induced Myocardial Depression
Zhang TN, Goodwin JE, Liu B, Li D, Wen R, Yang N, Xia J, Zhou H, Zhang T, Song WL, Liu CF. Characterization of Long Noncoding RNA and mRNA Profiles in Sepsis-Induced Myocardial Depression. Molecular Therapy - Nucleic Acids 2019, 17: 852-866. PMID: 31472370, PMCID: PMC6722300, DOI: 10.1016/j.omtn.2019.07.020.Peer-Reviewed Original ResearchGene Ontology term enrichmentMRNA profilesCell apoptosisMyocardial depressionBasic molecular mechanismsLong noncoding RNAPVT1 geneTerm enrichmentNoncoding RNAsRNA sequencingSeptic shockNovel lncRNAMolecular mechanismsRat modelLncRNAsFunctional roleRelated pathwaysC-MycHypodynamic septic shockCaspase-3Intensive care unitExpression of MyD88Bcl-2ApoptosisLeft ventricular tissueCharacterization of Circular RNA and microRNA Profiles in Septic Myocardial Depression: a Lipopolysaccharide-Induced Rat Septic Shock Model
Zhang TN, Yang N, Goodwin JE, Mahrer K, Li D, Xia J, Wen R, Zhou H, Zhang T, Song WL, Liu CF. Characterization of Circular RNA and microRNA Profiles in Septic Myocardial Depression: a Lipopolysaccharide-Induced Rat Septic Shock Model. Inflammation 2019, 42: 1990-2002. PMID: 31332662, DOI: 10.1007/s10753-019-01060-8.Peer-Reviewed Original ResearchConceptsCircular RNAsDifferential expressionGene Ontology term enrichmentFeatures of circRNAsMiRNA-mRNA networkMicroRNA profilesBasic molecular mechanismsNovel miRNAsCellular functionsRegulatory networksTerm enrichmentRNA sequencingBioinformatics analysisComprehensive circRNARegulator networkRegulatory relationshipsMolecular mechanismsCircRNAsMetabolic processesMiRNAsHeart tissueBiological mechanismsMiRNARNAPathological processes