2021
Brief original report: Does smoking status provide information relevant to screening for other substance use among US adults?
Khan MR, Ban K, Caniglia EC, Edelman JE, Gaither J, Crystal S, Chichetto NE, Young KE, Tate J, Justice AC, Braithwaite RS. Brief original report: Does smoking status provide information relevant to screening for other substance use among US adults? Preventive Medicine Reports 2021, 23: 101483. PMID: 34345578, PMCID: PMC8319511, DOI: 10.1016/j.pmedr.2021.101483.Peer-Reviewed Original ResearchInjection drug useUnhealthy alcohol useTobacco screeningDrug useSubstance useOpioid useStimulant useAlcohol useCrack/cocaine useIllicit opioid useCrack/cocaineTest performance characteristicsFormer smokersCurrent smokingSmoking statusUS adultsLifetime smokingCocaine useSmokingScreening resultsFour-fold decreaseNegative resultsMarijuana usePositive resultsTwo-fold decreaseAssociation of Syndemic Unhealthy Alcohol Use, Smoking, and Depressive Symptoms on Incident Cardiovascular Disease among Veterans With and Without HIV-Infection
Chichetto NE, Kundu S, Freiberg MS, Koethe JR, Butt AA, Crystal S, So-Armah KA, Cook RL, Braithwaite RS, Justice AC, Fiellin DA, Khan M, Bryant KJ, Gaither JR, Barve SS, Crothers K, Bedimo RJ, Warner A, Tindle HA. Association of Syndemic Unhealthy Alcohol Use, Smoking, and Depressive Symptoms on Incident Cardiovascular Disease among Veterans With and Without HIV-Infection. AIDS And Behavior 2021, 25: 2852-2862. PMID: 34101074, PMCID: PMC8376776, DOI: 10.1007/s10461-021-03327-4.Peer-Reviewed Original ResearchConceptsIncident cardiovascular diseaseUnhealthy alcohol useCardiovascular diseaseDepressive symptomsCVD riskHIV statusAlcohol useMultivariable Cox proportional hazards regressionCases of CVDCox proportional hazards regressionCVD-free participantsHIV-negative veteransProportional hazards regressionHIV-negativeHIV infectionHazards regressionSyndemic conditionsExcess riskRisk factorsDiagnostic codesHigh prevalenceObservational studyBaseline numberGreater riskSmoking
2020
Does Reducing Drinking in Patients with Unhealthy Alcohol Use Improve Pain Interference, Use of Other Substances, and Psychiatric Symptoms?
Caniglia EC, Stevens ER, Khan M, Young KE, Ban K, Marshall BDL, Chichetto NE, Gaither JR, Crystal S, Edelman EJ, Fiellin DA, Gordon AJ, Bryant KJ, Tate J, Justice AC, Braithwaite RS. Does Reducing Drinking in Patients with Unhealthy Alcohol Use Improve Pain Interference, Use of Other Substances, and Psychiatric Symptoms? Alcohol Clinical And Experimental Research 2020, 44: 2257-2265. PMID: 33030753, PMCID: PMC8077101, DOI: 10.1111/acer.14455.Peer-Reviewed Original ResearchConceptsUnhealthy alcohol useAlcohol usePain interferenceTobacco smokingUS veteransOdds ratioPsychiatric symptomsDepressive symptomsCocaine useVeterans Aging Cohort StudyAlcohol Use Disorders Identification Test (AUDIT) questionnaireCannabis useSubstance useAging Cohort StudyAnxiety symptomsSeparate logistic regression modelsChronic pain interferenceMultisite observational studyLogistic regression modelsCohort studyInverse probability weightingNext followObservational studyPotential selection biasYears postbaseline
2019
High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans.
Banerjee G, Edelman EJ, Barry DT, Crystal S, Gordon KS, Gordon AJ, Gaither JR, Green TC, Kerns RD, Manhapra A, Moore BA, Fiellin DA, Marshall BDL. High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans. Pain 2019, 160: 2126-2135. PMID: 31145217, PMCID: PMC6699915, DOI: 10.1097/j.pain.0000000000001606.Peer-Reviewed Original ResearchConceptsHigh-dose opioid prescriptionsOpioid prescriptionsHeroin useCohort studyPrior receiptHepatitis C virus (HCV) infection statusLong-term opioid prescriptionsPast-year heroin useVeterans Aging Cohort StudyHigh-dose opioidsOpioid-prescribing patternsProspective cohort studyAging Cohort StudyOpioid use disorderCurrent national guidelinesUnhealthy alcohol useUnited States veteransUnited States military veteransVirus infection statusPosttraumatic stress disorderOpioid receiptPrescribed opioidsPain interferenceCox regressionStates veteransAssociation of Syndemic Unhealthy Alcohol Use, Cigarette Use, and Depression With All-Cause Mortality Among Adults Living With and Without HIV Infection: Veterans Aging Cohort Study
Chichetto NE, Kundu S, Freiberg MS, Butt AA, Crystal S, So-Armah KA, Cook RL, Braithwaite RS, Fiellin DA, Khan MR, Bryant KJ, Gaither JR, Barve SS, Crothers K, Bedimo RJ, Warner AL, Tindle HA, Study V. Association of Syndemic Unhealthy Alcohol Use, Cigarette Use, and Depression With All-Cause Mortality Among Adults Living With and Without HIV Infection: Veterans Aging Cohort Study. Open Forum Infectious Diseases 2019, 6: ofz188. PMID: 31211153, PMCID: PMC6559272, DOI: 10.1093/ofid/ofz188.Peer-Reviewed Original ResearchVeterans Aging Cohort StudyAging Cohort StudyCigarette useHealth statusUninfected participantsCause mortalityCohort studyHIV statusMortality riskUnhealthy drinkingMultivariable Cox proportional hazards regressionCox proportional hazards regressionAdjusted hazard ratioHIV disease progressionProportional hazards regressionUnhealthy alcohol useHigher mortality riskCo-occurring conditionsUninfected veteransHazard ratioObservational cohortHIV infectionHazards regressionDisease progressionBaseline cancer
2018
Alcohol and Mortality
Eyawo O, McGinnis KA, Justice AC, Fiellin DA, Hahn JA, Williams EC, Gordon AJ, Marshall BDL, Kraemer KL, Crystal S, Gaither JR, Edelman EJ, Bryant KJ, Tate JP. Alcohol and Mortality. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2018, 77: 135-143. PMID: 29112041, PMCID: PMC5762259, DOI: 10.1097/qai.0000000000001588.Peer-Reviewed Original ResearchConceptsHepatitis C virusAlcohol exposureAlcohol useDirect biomarkerVeterans Aging Cohort Study Biomarker CohortBlood collection dateRecent alcohol exposureHIV viral suppressionUnhealthy alcohol useRelationship of alcoholAUDIT-C scoresViral suppressionC virusHigh riskRisk of harmHIVClinical settingMortalityPEthExposureBiomarkersRiskImproved detectionAuditIndividualsRacial/ethnic differences in the association between alcohol use and mortality among men living with HIV
Bensley KM, McGinnis KA, Fiellin DA, Gordon AJ, Kraemer KL, Bryant KJ, Edelman EJ, Crystal S, Gaither JR, Korthuis PT, Marshall BDL, Ornelas IJ, Chan KCG, Dombrowski JC, Fortney JC, Justice AC, Williams EC. Racial/ethnic differences in the association between alcohol use and mortality among men living with HIV. Addiction Science & Clinical Practice 2018, 13: 2. PMID: 29353555, PMCID: PMC6389249, DOI: 10.1186/s13722-017-0103-z.Peer-Reviewed Original ResearchConceptsLow-risk alcohol useMortality riskAlcohol useRace/ethnicityWhite PLWHMortality rateAlcohol Use Disorders Identification Test-Consumption (AUDIT-C) questionnaireVeterans Aging Cohort StudyCox proportional hazards modelHigh-risk alcohol useAUDIT-C screeningAging Cohort StudyElectronic health record dataRisk of mortalityHigh-risk relativesUnhealthy alcohol useHigher mortality riskProportional hazards modelHealth record dataHigh mortality rateEthnic groupsMale PLWHCohort studyWhite patientsGeneral outpatients
2017
Association of Cannabis, Stimulant, and Alcohol use with Mortality Prognosis Among HIV-Infected Men
Adams JW, Bryant KJ, Edelman J, Fiellin DA, Gaither JR, Gordon AJ, Gordon KS, Kraemer KL, Mimiaga MJ, Operario D, Tate JP, van den Berg JJ, Justice AC, Marshall BDL. Association of Cannabis, Stimulant, and Alcohol use with Mortality Prognosis Among HIV-Infected Men. AIDS And Behavior 2017, 22: 1341-1351. PMID: 28887669, PMCID: PMC5881942, DOI: 10.1007/s10461-017-1905-4.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyLow-risk alcohol useRisk alcohol useMortality riskAlcohol useStimulant useAdjusted longitudinal analysesAging Cohort StudyUnhealthy alcohol useAssociation of cannabisVACS IndexCause mortalityCohort studyPatient populationPrognostic indicatorMortality prognosisHIVStudy periodSubstance useCannabisRiskLongitudinal analysisMenMortalityStimulants