Featured Publications
Vaccination With Leptospira interrogans PF07598 Gene Family-Encoded Virulence Modifying Proteins Protects Mice From Severe Leptospirosis and Reduces Bacterial Load in the Liver and Kidney
Chaurasia R, Salovey A, Guo X, Desir G, Vinetz JM. Vaccination With Leptospira interrogans PF07598 Gene Family-Encoded Virulence Modifying Proteins Protects Mice From Severe Leptospirosis and Reduces Bacterial Load in the Liver and Kidney. Frontiers In Cellular And Infection Microbiology 2022, 12: 926994. PMID: 35837473, PMCID: PMC9274288, DOI: 10.3389/fcimb.2022.926994.Peer-Reviewed Original ResearchConceptsLethal challenge infectionChallenge infectionBacterial loadC3H/HeJ miceKey target organClinical pathogenesisSevere leptospirosisOrgan infectionProtein immunizationHeJ miceSerovar CanicolaTarget organsAnimal modelsLeptospirosis pathogenesisCellular pathogenesisMicePathogenesisInfectionLeptospira interrogansVirulence factorsModifying proteinsImmunizationKidneyLeptospirosisLiver
1989
Interdependence of CD4+ T cells and malarial spleen in immunity to Plasmodium vinckei vinckei. Relevance to vaccine development.
Kumar S, Good M, Dontfraid F, Vinetz J, Miller L. Interdependence of CD4+ T cells and malarial spleen in immunity to Plasmodium vinckei vinckei. Relevance to vaccine development. The Journal Of Immunology 1989, 143: 2017-23. PMID: 2570802, DOI: 10.4049/jimmunol.143.6.2017.Peer-Reviewed Original ResearchConceptsBALB/c micePlasmodium vinckei vinckeiT cellsImmune miceC miceVivo depletionSpleen cellsNaive BALB/cAthymic nu/nu miceBALB/c nude miceC3H/HeN miceNu/nu miceImmune spleen cellsBALB/cLoss of immunityImmune CD4Malaria AgMalarial spleenVivo CD4Adoptive transferImmune spleenSplenectomized miceMalaria vaccineRodent malariaHeN mice