Estramustine sensitizes human glioblastoma cells to irradiation.
Yoshida D, Piepmeier J, Weinstein M. Estramustine sensitizes human glioblastoma cells to irradiation. Cancer Research 1994, 54: 1415-7. PMID: 8137240.Peer-Reviewed Original ResearchConceptsMicroM estramustineRadiation enhancerGlioma cellsEffect of estramustineGlioblastoma cellsG2M cellsConcentration-dependent inhibitionMalignant glioma cellsHuman glioma cellsMinimal systemic toxicityEstramustineHuman glioblastoma cellsPotentiation factorSystemic toxicityG2M fractionFlow cytometryClonogenic survivalAntimicrotubule agentsCytotoxic effectsControl cellsH treatmentDaily scheduleCellsCell cycleRadiation sensitivity