2022
Prognostic mutational subtyping in de novo diffuse large B-cell lymphoma
Kim E, Jiang Y, Xu T, Bazeos A, Knapp A, Bolen C, Humphrey K, Nielsen T, Penuel E, Paulson J. Prognostic mutational subtyping in de novo diffuse large B-cell lymphoma. BMC Cancer 2022, 22: 231. PMID: 35236331, PMCID: PMC8892802, DOI: 10.1186/s12885-022-09237-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBridged Bicyclo Compounds, HeterocyclicClinical Trials, Phase II as TopicClinical Trials, Phase III as TopicEnhancer of Zeste Homolog 2 ProteinExome SequencingFemaleHumansLymphoma, Large B-Cell, DiffuseMaleMiddle AgedMutationPrognosisProto-Oncogene Proteins c-bcl-2RNA-SeqSulfonamidesTreatment OutcomeConceptsSequence dataWhole-exome sequencing dataExome-sequencing dataTargeted sequencing platformsExome sequencing dataTargeted sequencing dataBackgroundDiffuse large B-cell lymphomaLarge B-cell lymphomaSequencing platformsRNA-seqDe novo DLBCLImproved overall survivalTarget sequenceB-cell lymphomaVenetoclax therapyMutation subtypesPrognostic subsetsMutationsOverall survivalMolecular subsetsSubset distributionMutation groupSurvival outcomesMutation profilesClinical associations
2018
Meta-analysis of the lung microbiota in pulmonary tuberculosis
Hong B, Paulson J, Stine O, Weinstock G, Cervantes J. Meta-analysis of the lung microbiota in pulmonary tuberculosis. Tuberculosis 2018, 109: 102-108. PMID: 29559113, DOI: 10.1016/j.tube.2018.02.006.Peer-Reviewed Original ResearchConceptsSpecies signatureNext generation sequencing dataLung microbiotaGeneration sequencing dataClustering of microbiotaMycobacterium tuberculosisCaulobacter henriciiLung microbiota compositionSequence dataBody nichesR. mucilaginosaMicrobiota compositionSputum microbiotaActinomyces graevenitziiBioinformatics analysisMicrobiotaRothia mucilaginosaTB patientsHealthy controlsTB casesAssociated with pulmonary TBHaemophilus parahaemolyticusMeta-analysisLower respiratory tractBody sites