1994
Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis.
Marx M, Perlmutter R, Madri J. Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis. Journal Of Clinical Investigation 1994, 93: 131-139. PMID: 7506710, PMCID: PMC293745, DOI: 10.1172/jci116936.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueAnimalsCell DivisionCells, CulturedElectrophoresis, Polyacrylamide GelEndothelium, VascularEpididymisImmunoblottingKineticsMaleMicrocirculationMolecular WeightNeovascularization, PathologicPlatelet-Derived Growth FactorRatsReceptors, Platelet-Derived Growth FactorRecombinant ProteinsTime FactorsConceptsMicrovascular endothelial cellsEndothelial cellsPDGF receptorReceptor expressionPlatelet-derived growth factor receptor expressionGrowth factor receptor expressionPDGF receptor expressionFactor receptor expressionPDGF receptor alphaReceptor surface expressionEndothelial cell growthNovel therapeutic applicationsCell growthSuramin treatmentProliferative responseEndothelial cell phenotypeReceptor alphaPDGF isoformsPDGF-AAInhibited proliferationReceptor regulationPDGF-BBPDGF-ABAngiogenesisCell proliferation
1990
A 48 kDa collagen-binding phosphoprotein isolated from bovine aortic endothelial cells interacts with the collagenous domain, but not the globular domain, of collagen type IV
Yannariello-Brown J, Madri J. A 48 kDa collagen-binding phosphoprotein isolated from bovine aortic endothelial cells interacts with the collagenous domain, but not the globular domain, of collagen type IV. Biochemical Journal 1990, 265: 383-392. PMID: 2154186, PMCID: PMC1136898, DOI: 10.1042/bj2650383.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortaCattleCell MembraneCells, CulturedChromatography, AffinityChymotrypsinCollagenElectrophoresis, Gel, Two-DimensionalElectrophoresis, Polyacrylamide GelEndothelium, VascularFluorescent Antibody TechniqueImmune SeraMolecular WeightPeptide MappingPhosphoproteinsReceptors, Cell SurfaceReceptors, CollagenConceptsBovine aortic endothelial cellsSDS/PAGENon-equilibrium pH gel electrophoresisCollagen type IVCollagenous domainTwo-dimensional gel systemAortic endothelial cellsAdhesion assaysCell surface populationIndirect immunofluorescence experimentsGlobular NC1 domainCell surface labelingCollagen-binding proteinsChymotryptic peptide mapsEndothelial cellsGlobular domainIntracellular transportMinor isoformIndividual isoformsImmunofluorescence experimentsMolecular massGolgi regionCollagenous regionCell surfacePeptide maps
1989
Dispase, a Neutral Protease From Bacillus Polymyxa, Is a Powerful Fibronectinase and Type IV Collagenase
Stenn K, Link R, Moellmann G, Madri J, Kuklinska E. Dispase, a Neutral Protease From Bacillus Polymyxa, Is a Powerful Fibronectinase and Type IV Collagenase. Journal Of Investigative Dermatology 1989, 93: 287-290. PMID: 2546994, DOI: 10.1111/1523-1747.ep12277593.Peer-Reviewed Original ResearchBasement MembraneCollagenElectrophoresis, Polyacrylamide GelEndopeptidasesFibronectinsHumansInfant, NewbornMaleMicrobial CollagenaseSkin
1985
Characterization of the tissue form of type V collagen from chick bone.
Broek D, Madri J, Eikenberry E, Brodsky B. Characterization of the tissue form of type V collagen from chick bone. Journal Of Biological Chemistry 1985, 260: 555-562. PMID: 3965462, DOI: 10.1016/s0021-9258(18)89768-x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBone and BonesChickensCollagenElectrophoresis, Polyacrylamide GelLathyrismMercaptoethanolMicroscopy, ElectronMolecular WeightProtein DenaturationThermodynamicsConceptsSodium dodecyl sulfate-polyacrylamide gel electrophoresisDodecyl sulfate-polyacrylamide gel electrophoresisSulfate-polyacrylamide gel electrophoresisGlobular domainType V collagenCyanogen bromide peptide mapsTriple-helical domainGel electrophoresisIsolated alpha chainHelical domainTriple helixForm of alphaBanding patternsChick bonePeptide mapsProtein bandsBacterial collagenase digestionTerminal peptidesRotary shadowingHigh molecular weight formAlpha chainTissue formMolecular weight formsSlower mobilityHelix
1982
Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment.
Rao C, Margulies I, Tralka T, Terranova V, Madri J, Liotta L. Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment. Journal Of Biological Chemistry 1982, 257: 9740-9744. PMID: 7107589, DOI: 10.1016/s0021-9258(18)34135-8.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarcinoma, Squamous CellCell LineChemical PhenomenaChemistryCollagenElectrophoresis, Polyacrylamide GelGlycoproteinsHumansLamininMiceMicroscopy, ElectronNeoplasm ProteinsNeoplasms, ExperimentalThrombinConceptsElectron microscopySubunits of lamininGlobular end regionsBeta subunitLaminin short armsTumor cellsWhole laminin moleculeAlpha subunitSquamous carcinoma cellsHuman squamous carcinoma cellsMicroscopyCell attachmentLaminin moleculeAttachment propertiesCarcinoma cellsTumor cell attachmentBasement membraneLong armAlpha-thrombinType V Collagens of the Human Placenta: Trimer α-Chain Composition, Ultrastructural Morphology and Peptide Analysis
Madri J, Foellmer H, Furthmayr H. Type V Collagens of the Human Placenta: Trimer α-Chain Composition, Ultrastructural Morphology and Peptide Analysis. Collagen And Related Research 1982, 2: 19-29. PMID: 7105646, DOI: 10.1016/s0174-173x(82)80038-1.Peer-Reviewed Original ResearchMeSH KeywordsChymotrypsinCollagenElectrophoresis, Polyacrylamide GelFemaleHumansMacromolecular SubstancesMicroscopy, ElectronMicrovilliPeptide FragmentsPlacentaPregnancy