1998
Three-dimensional Type I Collagen Lattices Induce Coordinate Expression of Matrix Metalloproteinases MT1-MMP and MMP-2 in Microvascular Endothelial Cells*
Haas T, Davis S, Madri J. Three-dimensional Type I Collagen Lattices Induce Coordinate Expression of Matrix Metalloproteinases MT1-MMP and MMP-2 in Microvascular Endothelial Cells*. Journal Of Biological Chemistry 1998, 273: 3604-3610. PMID: 9452488, DOI: 10.1074/jbc.273.6.3604.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCells, CulturedCollagenDrug CombinationsEndothelium, VascularEnzyme ActivationEnzyme InhibitorsGelatinasesLamininMatrix Metalloproteinase 2Matrix Metalloproteinases, Membrane-AssociatedMetalloendopeptidasesNeovascularization, PhysiologicProtein ConformationProteoglycansRatsRats, Sprague-DawleyRNA, MessengerSignal TransductionTissue Inhibitor of Metalloproteinase-2ConceptsMT1-MMPTwo-dimensional cultureEndothelial cellsThree-dimensional collagen matrixEndothelial cell organizationEndothelial cell angiogenesisEndothelial cell migrationCell organizationCoordinate expressionPutative activatorMT1-MMP activationMMP-2Matrix metalloproteinasesCell migrationFunctional roleMatrix interactionsMatrix remodelingCollagen matrixCell angiogenesisEndothelial cell networksMMP-2 proteinProtein
1997
Involvement of endothelial PECAM-1/CD31 in angiogenesis.
DeLisser H, Christofidou-Solomidou M, Strieter R, Burdick M, Robinson C, Wexler R, Kerr J, Garlanda C, Merwin J, Madri J, Albelda S. Involvement of endothelial PECAM-1/CD31 in angiogenesis. American Journal Of Pathology 1997, 151: 671-7. PMID: 9284815, PMCID: PMC1857836.Peer-Reviewed Original ResearchMeSH KeywordsAngiotensin-Converting Enzyme InhibitorsAnimalsAntibodies, MonoclonalCells, CulturedCollagenCorneaDrug CombinationsEndotheliumFibroblast Growth Factor 2HumansLamininMiceMice, Inbred C57BLNeovascularization, PhysiologicPlatelet Endothelial Cell Adhesion Molecule-1ProteoglycansRatsRats, Sprague-DawleyTransforming Growth Factor betaConceptsCell-cell adhesion moleculesEndothelial cell-cell adhesion moleculesBasic fibroblast growth factorRat capillary endothelial cellsPECAM-1Adhesion moleculesHuman PECAM-1Murine PECAM-1Endothelial cellsFibroblast growth factorAdhesion receptorsProcess of angiogenesisPECAM-1/CD31Tube formationAdhesive interactionsVessel growthGrowth factorCapillary endothelial cellsPolyclonal antibodiesRat corneal neovascularizationAngiogenesisCorneal neovascularizationCellsMurine modelMonoclonal antibodies