1992
Acidic fibroblast growth factor-Pseudomonas exotoxin chimeric protein elicits antiangiogenic effects on endothelial cells.
Merwin J, Lynch M, Madri J, Pastan I, Siegall C. Acidic fibroblast growth factor-Pseudomonas exotoxin chimeric protein elicits antiangiogenic effects on endothelial cells. Cancer Research 1992, 52: 4995-5001. PMID: 1381275.Peer-Reviewed Original ResearchMeSH KeywordsADP Ribose TransferasesAmino Acid SequenceAnimalsBacterial ToxinsCell MovementCell SurvivalCells, CulturedEndothelium, VascularExotoxinsFibroblast Growth Factor 1In Vitro TechniquesMolecular Sequence DataNeovascularization, PathologicRatsRats, Inbred StrainsReceptors, Cell SurfaceReceptors, Fibroblast Growth FactorRecombinant Fusion ProteinsVirulence FactorsConceptsGrowth factor beta 1Endothelial cellsChimeric toxinBeta 1Inhibitory effectDose-dependent toxic effectAnti-angiogenic agentsMicrovascular endothelial cellsAcidic fibroblast growth factorFibroblast growth factorSignificant inhibitory effectMicrovascular endotheliumAntiangiogenic effectsPseudomonas exotoxinTumor cell linesAntimigratory effectsGrowth factorAngiogenic responseProtein synthesisCell linesFGF receptorsToxic effectsCell deathEndotheliumCell viability analysis
1990
Transforming growth factor beta1 modulates extracellular matrix organization and cell‐cell junctional complex formation during in vitro angiogenesis
Merwin J, Anderson J, Kocher O, Van Itallie C, Madri J. Transforming growth factor beta1 modulates extracellular matrix organization and cell‐cell junctional complex formation during in vitro angiogenesis. Journal Of Cellular Physiology 1990, 142: 117-128. PMID: 1688859, DOI: 10.1002/jcp.1041420115.Peer-Reviewed Original Research
1989
Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin.
Madri J, Reidy M, Kocher O, Bell L. Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin. Laboratory Investigation 1989, 60: 755-65. PMID: 2659888.Peer-Reviewed Original ResearchAnimalsBlotting, NorthernCarotid ArteriesCatheterizationCell DivisionCell MovementCells, CulturedCollagenCulture MediaEndothelium, VascularEnzyme-Linked Immunosorbent AssayFibronectinsImmunologic TechniquesMicroscopy, ElectronMicroscopy, Electron, ScanningRatsRats, Inbred StrainsRNA, MessengerTransforming Growth Factors
1988
Distribution of a 69-kD laminin-binding protein in aortic and microvascular endothelial cells: modulation during cell attachment, spreading, and migration.
Yannariello-Brown J, Wewer U, Liotta L, Madri J. Distribution of a 69-kD laminin-binding protein in aortic and microvascular endothelial cells: modulation during cell attachment, spreading, and migration. Journal Of Cell Biology 1988, 106: 1773-1786. PMID: 2967300, PMCID: PMC2115051, DOI: 10.1083/jcb.106.5.1773.Peer-Reviewed Original Research
1987
Retinol and extracellular collagen matrices modulate hepatic Ito cell collagen phenotype and cellular retinol binding protein levels.
Davis B, Pratt B, Madri J. Retinol and extracellular collagen matrices modulate hepatic Ito cell collagen phenotype and cellular retinol binding protein levels. Journal Of Biological Chemistry 1987, 262: 10280-10286. PMID: 3301832, DOI: 10.1016/s0021-9258(18)61109-3.Peer-Reviewed Original ResearchType I and type III procollagen peptides during hepatic fibrogenesis. An immunohistochemical and ELISA serum study in the CCl4 rat model.
Davis B, Madri J. Type I and type III procollagen peptides during hepatic fibrogenesis. An immunohistochemical and ELISA serum study in the CCl4 rat model. American Journal Of Pathology 1987, 126: 137-47. PMID: 2433943, PMCID: PMC1899545.Peer-Reviewed Original ResearchConceptsDays of treatmentSGPT valuesHepatic fibrogenesisSerum assaysProcollagen peptideType IHepatic collagen depositionUseful clinical indicatorCCl4 rat modelCarbon tetrachloride modelExtracellular collagen degradationHistologic inflammationSGPT levelsClinical indicatorsHepatic fibrosisHistologic fibrosisRat modelRoutine histologicSerum studiesClinical utilityCollagen depositionLinear regression analysisNormal levelsELISA assaysImmunofluorescent staining
1986
Endothelial cell proliferation during angiogenesis. In vitro modulation by basement membrane components.
Form D, Pratt B, Madri J. Endothelial cell proliferation during angiogenesis. In vitro modulation by basement membrane components. Laboratory Investigation 1986, 55: 521-30. PMID: 2430138.Peer-Reviewed Original Research
1985
Neoplastic disorganization of pancreatic epithelial cell-cell relations. Role of basement membrane.
Ingber D, Madri J, Jamieson J. Neoplastic disorganization of pancreatic epithelial cell-cell relations. Role of basement membrane. American Journal Of Pathology 1985, 121: 248-60. PMID: 4061565, PMCID: PMC1888057.Peer-Reviewed Original Research