1997
T cell adhesion to endothelial cells and extracellular matrix is modulated upon transendothelial cell migration.
Romanic A, Graesser D, Baron J, Visintin I, Janeway C, Madri J. T cell adhesion to endothelial cells and extracellular matrix is modulated upon transendothelial cell migration. Laboratory Investigation 1997, 76: 11-23. PMID: 9010446.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCell AdhesionCell MovementCells, CulturedCollagenEncephalomyelitis, Autoimmune, ExperimentalEndothelium, VascularExtracellular MatrixFibronectinsFlow CytometryIntegrin alpha4beta1IntegrinsIntercellular Adhesion Molecule-1Interleukin-2Lymphocyte Function-Associated Antigen-1MiceMice, Inbred StrainsMyelin Basic ProteinPeptide FragmentsReceptors, Lymphocyte HomingReceptors, Very Late AntigenRecombinant ProteinsT-LymphocytesUp-RegulationVascular Cell Adhesion Molecule-1ConceptsAdhesion molecule-1T cellsMolecule-1Recombinant vascular cell adhesion molecule-1Recombinant intercellular adhesion molecule-1Experimental autoimmune encephalomyelitis (EAE) miceLate activation antigen-4Vascular cell adhesion molecule-1Intercellular adhesion molecule-1Cell adhesion molecule-1T cell migrationExtracellular matrixCell migrationTransendothelial cell migrationAntigen-4Integrin surface expressionInflammatory responseCD4 expressionBrain sectionsT cell adhesionPerivascular tissueEndothelial cellsIntegrin expressionCell-ECM interactionsSurface expression
1994
Extracellular Matrix‐Degrading Proteinases in the Nervous System
Romanic A, Madri J. Extracellular Matrix‐Degrading Proteinases in the Nervous System. Brain Pathology 1994, 4: 145-156. PMID: 8061860, DOI: 10.1111/j.1750-3639.1994.tb00825.x.Peer-Reviewed Original ResearchConceptsCell-ECM interactionsExtracellular matrixMatrix-degrading proteinasesNeuronal cell migrationExtracellular matrix-degrading proteinasesCell migrationNervous systemECM degradationNeurite outgrowthCell proliferationDrug designProteolytic activityNew insightsPathological conditionsBrain tumor growthTumor growthMatrix metalloproteinasesProteinasesForm of therapyCentral nervous systemInhibitorsPlasminogen activatorTraffickingLeukocyte traffickingNerve demyelination