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INFORMATION FOR

    Joseph N. Contessa, MD, PhD

    Professor Adjunct of Therapeutic Radiology
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    Professor Adjunct of Therapeutic Radiology

    Biography

    Joseph N. Contessa, MD, PhD, a radiation oncologist, is the director of Yale Medicine’s Central Nervous System Radiotherapy Program. He specializes in treating patients with primary tumors of the brain, head and neck, and at the base of the skull.

    “Due to Yale's large referral base, I frequently see relatively rare tumors,” he says, including low-grade and malignant gliomas, ependymomas, high-grade meningiomas, hemangiopericytomas, paragangliomas, and schwannomas. His expertise in treating uncommon cancers benefits patients diagnosed with these tumor types. “I look forward to helping patients have the best possible outcome when they are faced with a challenging diagnosis,” he says.

    Dr. Contessa is a Professor of therapeutic radiology and of pharmacology at Yale School of Medicine where he is part of a team of physicians and scientists who are actively researching the cellular mechanisms that tumors use to evade or “outsmart” standard cancer therapies in hopes of identifying new approaches that improve treatment.

    “We are all working together to increase our knowledge, improve our care and beat cancer,” Dr. Contessa says.

    Last Updated on April 07, 2025.

    Appointments

    Education & Training

    Resident
    The University of Michigan (2009)
    Intern
    The University of Michigan (2005)
    PhD
    Medical College of Virginia Commonwealth Universit (2004)
    MD
    Medical College of Virginia Commonwealth Universit (2004)

    Research

    Overview

    Therapeutic approaches for the treatment of EGFR and FGFR addicted lung cancer

    Radiosensitization of malignant gliomas

    Novel small molecule inhibitors of N-linked glycosylation

    Molecular Imaging of the Epidermal Growth Factor Receptor

    Drug Discovery and High Throughput Screening

    Targeted therapy for head and neck squamous cell carcinoma

    Medical Research Interests

    Chemicals and Drugs; Neoplasms; Radiobiology

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Joseph N. Contessa's published research.

    Publications

    2025

    2024

    2023

    2021

    2019

    Clinical Trials

    Current Trials

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