2024
Total Shoulder Arthroplasty in Patients With Hemophilia A: Greater Odds of Postoperative Bleeding and Thromboembolic Events but No Difference in 5-year Implant Survival.
Gillinov S, Modrak M, Park N, Monahan P, Wilhelm C, Lee M, Mahatme R, Fong S, Moran J, Grauer J, Jimenez A. Total Shoulder Arthroplasty in Patients With Hemophilia A: Greater Odds of Postoperative Bleeding and Thromboembolic Events but No Difference in 5-year Implant Survival. Clinical Orthopaedics And Related Research® 2024 PMID: 39246053, DOI: 10.1097/corr.0000000000003209.Peer-Reviewed Original ResearchVenous thromboembolic eventsTotal shoulder arthroplastyHemophilia AImplant survivalMatched controlsThromboembolic eventsElixhauser Comorbidity IndexMale patientsAdverse eventsShoulder arthroplastyProsthesis survivalThromboembolic adverse eventsVenous thromboembolic event prophylaxisKaplan-Meier analysisFactor VIII levelsRevers total shoulder arthroplastyIndividual patient basisOdds of postoperative bleedingPostoperative bleedingBleeding complicationsTranexamic acidNinety-dayPatient basisControl cohortComorbidity indexAnatomic and reverse total shoulder arthroplasty: variables affecting 90-day overall reimbursement
Halperin S, Dhodapkar M, Modrak M, Donohue K, Medvecky M, Grauer J. Anatomic and reverse total shoulder arthroplasty: variables affecting 90-day overall reimbursement. Seminars In Arthroplasty JSES 2024, 34: 564-570. DOI: 10.1053/j.sart.2024.02.007.Peer-Reviewed Original ResearchAnatomic total shoulder arthroplastyReverse total shoulder arthroplastyTotal shoulder arthroplastyTotal shoulder arthroplasty patientsPostoperative eventsShoulder arthroplastyPatient demographicsOverall reimbursementSurgery typeAdverse eventsMale sexAssociated with reimbursementMultivariate linear regressionOncological diagnosisEmergency department visitsPatientsOrthopedic proceduresEffective procedureAdministrative databasesHospital readmissionInsurance typeSurgeryReduce healthcare expendituresDepartment visitsIncreased frequencyPrediction models for risk assessment of surgical site infection after spinal surgery: A systematic review
Lauinger A, Blake S, Fullenkamp A, Polites G, Grauer J, Arnold P. Prediction models for risk assessment of surgical site infection after spinal surgery: A systematic review. North American Spine Society Journal (NASSJ) 2024, 19: 100518. DOI: 10.1016/j.xnsj.2024.100518.Peer-Reviewed Original ResearchSurgical site infectionPreoperative risk modelSpinal surgerySite infectionAdverse eventsAssessment of surgical site infectionACS NSQIP surgical risk calculatorPostoperative surgical site infectionNSQIP surgical risk calculatorRate of adverse eventsSpine surgery patientsRisk of adverse eventsStratify patient riskSurgical risk calculatorField of spine surgeryClinical prediction toolSpine surgeryRisk modelSurgery patientsSurgeryAddressing factorsPatient riskClinical utilitySystematic reviewUnique susceptibilityP27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy
Gouzoulis M, Seddio A, Zhu J, Day W, Jabbouri S, Rubio D, Grauer J. P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy. The Spine Journal 2024, 24: s76. DOI: 10.1016/j.spinee.2024.06.048.Peer-Reviewed Original ResearchSevere adverse eventsHistory of renal transplantationUrinary tract infectionRenal transplantationAcute kidney injuryAdverse eventsMinor adverse eventsElixhauser Comorbidity IndexIncreased oddsCurrent Procedural TerminologyTract infectionsLumbar discectomyKidney injuryED visitsIncreased odds of acute kidney injuryOdds of acute kidney injuryOdds ratioOdds of ED visitsKaplan-Meier survival curvesDays of follow-upRenal transplant groupRenal transplant patientsIncidence of reoperationRisk of reoperationOdds of sepsisP116. National trends and risk factors for new-onset depression following posterior lumbar fusion
Day W, Gouzoulis M, Zhu J, Seddio A, Fourman M, Grauer J. P116. National trends and risk factors for new-onset depression following posterior lumbar fusion. The Spine Journal 2024, 24: s119. DOI: 10.1016/j.spinee.2024.06.138.Peer-Reviewed Original ResearchNew-onset depressionPosterior lumbar fusionNational administrative claims databaseSingle-level posterior lumbar fusionRisk factorsDevelopment of new-onset depressionAdministrative claims databasePostoperative complicationsLumbar fusionNational trendsFactors associated with patientsClaims databaseAggregate patient dataAdult patientsTarget risk mitigation strategiesMultivariate logistic regressionPsychiatric risk factorsPotential risk factorsElixhauser Comorbidity IndexPercentage of patientsHigher oddsCase-controlAlcohol/drug abuseDiagnosis of tumorsLogistic regressionP31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy
Seddio A, Gouzoulis M, Smith-Voudouris J, Rubio D, Day W, Grauer J. P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy. The Spine Journal 2024, 24: s78. DOI: 10.1016/j.spinee.2024.06.052.Peer-Reviewed Original ResearchTestosterone replacement therapyAcute kidney injuryLumbar discectomyAdverse eventsMale patientsOdds ratioCurrent Procedural TerminologyReoperation ratePostoperative outcomesElixhauser Comorbidity IndexPostoperative recoveryMultivariate analysisSingle-level lumbar discectomyTestosterone replacement therapy patientsMyocardial infarctionOrthopedic surgeryKaplan-Meier survival analysisEmergency departmentLumbar spinal proceduresLog-rank testMonths of surgeryRetrospective cohort studyPostoperative adverse eventsEnhanced postoperative recoveryMinor adverse events35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Ratnasamy P, Rubio D, Grauer J. 35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients. The Spine Journal 2024, 24: s19. DOI: 10.1016/j.spinee.2024.06.478.Peer-Reviewed Original ResearchAdverse eventsSpinal neurologic deficitsStatistically significant differenceCurrent Procedural TerminologyElixhauser Comorbidity IndexEpidural injectionAdult patientsNeurological deficitsAdverse outcomesMultivariate analysisED visitsIncidence of adverse eventsEpidural spinal injectionsTransforaminal epidural injectionsEmergency departmentTransforaminal (TFRisk of adverse eventsSignificant differenceRetrospective cohort studyMinor adverse eventsSampled adult patientsOutcome measures IncidencePotential adverse eventsSpinal injectionPatient age117. Opioid prescription patterns following single-level lumbar discectomy: a national database study
Rancu A, Gouzoulis M, Winter A, Katsnelson B, Ansah-Twum J, Grauer J. 117. Opioid prescription patterns following single-level lumbar discectomy: a national database study. The Spine Journal 2024, 24: s60-s61. DOI: 10.1016/j.spinee.2024.06.560.Peer-Reviewed Original ResearchMorphine milligram equivalentsSingle-level lumbar discectomyMedian morphine milligram equivalentsOpioid prescriptionsLumbar discectomyPrescribed morphine milligram equivalentsDiagnosis of chronic painPostoperative opioid prescriptionsOpioid prescribing patternsOpioid prescription patternsPostoperative pain controlPostoperative pain managementProportion of patientsNational database studyMultivariate linear regression analysisWilcoxon rank sum testDiagnosis of neoplasmsMultivariate logistic regressionRank sum testExcess opioidsPrescription percentageMilligram equivalentsPostoperative opioidsChronic painSpine procedures100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Zhu J, Rubio D, Grauer J. 100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024, 24: s52-s53. DOI: 10.1016/j.spinee.2024.06.543.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsImpact of semaglutideHospital readmissionPostoperative outcomesElixhauser Comorbidity IndexED visitsT2DM patientsCurrent Procedural TerminologyEmergency departmentLumbar fusionAdverse eventsOdds of hospital readmissionOutcome measures IncidenceRisk of type I errorInferior postoperative outcomesDiagnosis of T2DMMonths of surgeryYear of surgeryRetrospective cohort studyMinor adverse eventsType II diabetes mellitusMatched 1:4Management of diabetesTrends in management of odontoid fractures 2010–2021
Gouzoulis M, Seddio A, Rancu A, Jabbouri S, Moran J, Varthi A, Rubio D, Grauer J. Trends in management of odontoid fractures 2010–2021. North American Spine Society Journal (NASSJ) 2024, 100553. DOI: 10.1016/j.xnsj.2024.100553.Peer-Reviewed Original ResearchOutcomes following two-level Cervical Disc Arthroplasty Relative to two-level Anterior Cervical Discectomy.
Ratnasamy P, Gouzoulis M, Jabbouri S, Varthi A, Grauer J. Outcomes following two-level Cervical Disc Arthroplasty Relative to two-level Anterior Cervical Discectomy. Spine 2024 PMID: 39190404, DOI: 10.1097/brs.0000000000005131.Peer-Reviewed Original ResearchCervical disc arthroplasty patientsFive-year survivalCervical disc arthroplastyPostoperative adverse eventsSpine reoperationTwo-level cervical disc arthroplastyAdverse eventsACDF patientsPatient ageElixhauser Comorbidity IndexTreatment optionsMultivariate analysisDegenerative cervical spine pathologyTwo-level surgeryCervical spine pathologyTwo-level ACDFAnterior cervical discectomyNovel treatment optionsMinor adverse eventsCervical discectomyNo significant differenceSpine pathologyACDFReoperationComorbidity indexOne- versus Three-- Level Fusion in Patients Undergoing Multilevel Lumbar Decompression: Relative Perioperative Risks and Five-year Revisions.
Ratnasamy P, Gouzoulis M, Jabbouri S, Rubio D, Grauer J. One- versus Three-- Level Fusion in Patients Undergoing Multilevel Lumbar Decompression: Relative Perioperative Risks and Five-year Revisions. Spine 2024 PMID: 39190416, DOI: 10.1097/brs.0000000000005130.Peer-Reviewed Original ResearchOne-level fusionLumbar decompressionThree-level fusionPostoperative adverse eventsAdverse eventsOdds ratioElixhauser Comorbidity IndexPatient ageFive-year survivalOdds of perioperative complicationsLumbar decompression patientsPerioperative complicationsDecompression patientsPerioperative riskFusion patientsSpinal reoperationLumbar fusionReoperationComorbidity indexMultivariate analysisPatientsClinical interestDecompressionFusion levelsOddsOutcomes following total shoulder arthroplasty in patients with systemic lupus erythematosus
Salib A, Sanchez J, Huggins L, Seddio A, Dhodapkar M, Smith-Voudouris J, Norman M, Koumpouras F, Grauer J. Outcomes following total shoulder arthroplasty in patients with systemic lupus erythematosus. Journal Of Shoulder And Elbow Surgery 2024 PMID: 39154846, DOI: 10.1016/j.jse.2024.07.008.Peer-Reviewed Original ResearchSystemic lupus erythematosus patientsSystemic lupus erythematosusTotal shoulder arthroplastyAdverse eventsImplant survivalLupus erythematosusMultivariate analysisShoulder arthroplastyIncreased oddsTotal shoulder arthroplasty patientsNon-SLE patientsMultivariate logistic regressionImmunomodulatory therapyPostoperative complicationsElixhauser Comorbidity IndexAdult patientsNinety-dayUnivariate analysisSurgical planningComorbidity indexPatient counselingGlenohumeral osteoarthritisPatientsComorbid conditionsOrthopedic-relatedUtilization and timing of surgical intervention for central cord syndrome in the United States
Dhodapkar M, Halperin S, Seddio A, Dahodwala T, Rubio D, Grauer J. Utilization and timing of surgical intervention for central cord syndrome in the United States. European Spine Journal 2024, 1-7. PMID: 39103615, DOI: 10.1007/s00586-024-08431-2.Peer-Reviewed Original ResearchCentral cord syndromeSurgical interventionAbsence of bony injuryOperative interventionCord syndromeBony injuriesPredictors of operative managementAbsence of vertebral fracturesTiming of surgical interventionTiming of operative interventionCohort of patientsProportion of patientsDays of diagnosisHigher comorbidity burdenVertebral fracturesSpinal cord injuryMethodsAdult patientsNon-operativelyNonsurgical interventionsMultivariate analysisStudy assessed utilizationComorbidity burdenIncomplete spinal cord injuryPatientsInclusion criteriaRate and risk factors for inpatient falls following single-level posterior lumbar fusion: A national registry study
Gouzoulis M, Jabbouri S, Seddio A, Moran J, Day W, Ratnasamy P, Grauer J. Rate and risk factors for inpatient falls following single-level posterior lumbar fusion: A national registry study. North American Spine Society Journal (NASSJ) 2024, 100549. DOI: 10.1016/j.xnsj.2024.100549.Peer-Reviewed Original ResearchPosterior lumbar fusionSingle-level posterior lumbar fusionInpatient fallsOdds ratioLumbar fusionFall prevention programsIncidence of secondary injuryNational sample of patientsRisk factorsDecreased odds ratioPatient variablesPotential patient outcomesMultivariate logistic regressionNational registry studySample of patientsPrevention programsInpatient costsMedicaid insuranceActive deliriumAlcohol use disorderMethods Adult patientsSpinal pathologyOutcome metricsCommercial insuranceNational sampleRisk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty
Jayaram R, Day W, Gouzoulis M, Zhu J, Grauer J, Rubin L. Risk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty. Arthroplasty Today 2024, 28: 101440. PMID: 39139361, PMCID: PMC11320433, DOI: 10.1016/j.artd.2024.101440.Peer-Reviewed Original ResearchBody mass indexNerve injuryElixhauser Comorbidity IndexRisk factorsMultivariate analysisOdds ratioRisk of nerve injuryTotal hip arthroplastyRevision proceduresObese BMI statusUnderweight body mass indexDecreased odds ratioPatient ageSurgery typeRisk stratificationAdverse eventsBMI statusMass indexFemale sexAdverse outcomesComorbidity indexDecreased riskPatient counselingHip arthroplastyNerveA Nationwide Analysis of Complications, Reoperations and Cost of Wide-Awake Flexor Tendon Repairs.
Kammien A, Rancu A, Kim S, Parikh N, Grauer J, Colen D. A Nationwide Analysis of Complications, Reoperations and Cost of Wide-Awake Flexor Tendon Repairs. Plastic & Reconstructive Surgery 2024 PMID: 39026384, DOI: 10.1097/prs.0000000000011651.Peer-Reviewed Original ResearchElixhauser Comorbidity IndexWound complicationsTraditional anesthesiaEmergency department visitsYears of follow-upTendon repairAnalysis of complicationsRate of tendon ruptureNationwide cohort studyDepartment visitsWide-awake surgeryFlexor tendon repairConcomitant treatmentMatched cohortFollow-upZone II flexor tendon repairCohort studyMultivariate linear regressionAnesthesia techniquesComorbidity indexVascular injuryIntraoperative testingReoperationNerve repairPatientsThe Association of Surgical Setting With Opioid Prescribing Patterns Following Wide-Awake Trigger Finger Release.
Kammien A, Shvedova M, Allam O, Prsic A, Grauer J, Colen D. The Association of Surgical Setting With Opioid Prescribing Patterns Following Wide-Awake Trigger Finger Release. Annals Of Plastic Surgery 2024 PMID: 38984645, DOI: 10.1097/sap.0000000000004030.Peer-Reviewed Original ResearchPerioperative opioid prescriptionMorphine milligram equivalentsOpioid prescriptionsPain controlSurgical settingPostoperative painOffice-based surgeryOperating roomMultivariate analysisPerception of postoperative painOpioid prescribing patternsPostoperative pain controlReducing opioid prescriptionsNational administrative claims databaseElixhauser Comorbidity Index scoreChronic back/neck painHand surgeryComorbidity Index scoreAdministrative claims databaseMonitored anesthesia careMilligram equivalentsPostoperative dataPrescribed opioidsPerioperative opioidsPreoperative dataTrends in Open Versus Endoscopic Carpal Tunnel Release From 2010 to 2021
Ratnasamy P, Rudisill K, Joo P, Lattanza L, Grauer J. Trends in Open Versus Endoscopic Carpal Tunnel Release From 2010 to 2021. JAAOS Global Research And Reviews 2024, 8: e24.00077. PMID: 38885416, PMCID: PMC11191037, DOI: 10.5435/jaaosglobal-d-24-00077.Peer-Reviewed Original ResearchTotal Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. Total Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events. The Journal Of Arthroplasty 2024 PMID: 38838962, DOI: 10.1016/j.arth.2024.05.083.Peer-Reviewed Original ResearchFactor V LeidenAdverse eventsChemoprophylactic agentV LeidenMultivariate analysisFactor V Leiden patientsTotal hip arthroplastyPatients to venous thromboembolismLog-rank testIncreased VTE riskVenous thromboembolic eventsElevated riskPerioperative adverse eventsPre-existing comorbiditiesAdministrative claims databaseInherited thrombophiliaThromboembolic eventsElixhauser Comorbidity IndexAdult patientsVenous thromboembolismImplant survivalVTE riskComorbidity indexClaims databaseHip arthroplasty