2021
Abnormal FeV1 and body mass index are associated with impaired cough-related quality of life in sarcoidosis patients
Frye B, Potasso L, Farin E, Fichtner U, Birring S, Müller-Quernheim J, Schupp J. Abnormal FeV1 and body mass index are associated with impaired cough-related quality of life in sarcoidosis patients. Respiratory Medicine 2021, 188: 106600. PMID: 34530353, DOI: 10.1016/j.rmed.2021.106600.Peer-Reviewed Original ResearchConceptsLeicester Cough QuestionnaireCough-related qualityQuality of lifeSarcoidosis patientsLCQ scoreBody mass indexAbnormal FEV1Routine followLung functionOrgan impairmentTreatable traitsMass indexDisease burdenGranulomatous diseaseFEV1PatientsSarcoidosisBMIScoresQuestionnaireLungCohortFollowDiseaseLife
2018
Phenotypes of organ involvement in sarcoidosis
Schupp J, Freitag-Wolf S, Bargagli E, Mihailović-Vučinić V, Rottoli P, Grubanovic A, Müller A, Jochens A, Tittmann L, Schnerch J, Olivieri C, Fischer A, Jovanovic D, Filipovic S, Videnovic-Ivanovic J, Bresser P, Jonkers R, O'Reilly K, Ho L, Gaede K, Zabel P, Dubaniewicz A, Marshall B, Kieszko R, Milanowski J, Günther A, Weihrich A, Petrek M, Kolek V, Keane M, O'Beirne S, Donnelly S, Haraldsdottir S, Jorundsdottir K, Costabel U, Bonella F, Wallaert B, Grah C, Peroš-Golubičić T, Luisetti M, Kadija Z, Pabst S, Grohé C, Strausz J, Vašáková M, Sterclova M, Millar A, Homolka J, Slováková A, Kendrick Y, Crawshaw A, Wuyts W, Spencer L, Pfeifer M, Valeyre D, Poletti V, Wirtz H, Prasse A, Schreiber S, Krawczak M, Müller-Quernheim J. Phenotypes of organ involvement in sarcoidosis. European Respiratory Journal 2018, 51: 1700991. PMID: 29371378, DOI: 10.1183/13993003.00991-2017.Peer-Reviewed Original ResearchConceptsOrgan involvementIntrathoracic lymph node involvementAbdominal organ involvementLymph node involvementEuropean multicentre studySystemic granulomatous diseaseNew clinical phenotypeHitherto unknown etiologyAcute onsetExtrapulmonary involvementNode involvementSkin involvementFemale patientsMulticentre studyDisease involvementUnknown etiologyCaucasian patientsGranulomatous diseaseHomogenous cohortSarcoidosisPatientsClinical phenotypeStudy centersStandardised protocolDisease phenotype
2016
Sarkoidose
Frye B, Schupp J, Köhler T, Voll R, Müller-Quernheim J. Sarkoidose. Zeitschrift Für Rheumatologie 2016, 75: 389-401. PMID: 27146405, DOI: 10.1007/s00393-016-0086-2.ChaptersConceptsTumor necrosis factorLymph nodesEndobronchial ultrasound-guided fine-needle aspirationHigh spontaneous remission rateUltrasound-guided fine-needle aspirationSecond-line medicationsThird-line therapyHilar lymph nodesImportant differential diagnosisSpontaneous remission rateRare granulomatous diseaseFine-needle aspirationRemission rateAcute sarcoidosisOrgan impairmentRheumatic diseasesGranulomatous diseaseNecrosis factorDifferential diagnosisNeedle aspirationTherapeutic goalsDiagnostic clarificationSarcoidosisMedicationsTherapy
2015
Diagnostik und Therapie der Sarkoidose
Frye B, Schupp J, Köhler T, Müller-Quernheim J. Diagnostik und Therapie der Sarkoidose. Der Internist 2015, 56: 1346-1352. PMID: 26563335, DOI: 10.1007/s00108-015-3757-1.ChaptersConceptsIntrathoracic lymph nodesLymph nodesGranulomatous diseaseSteroid-refractory diseaseFurther therapeutic optionsNon-necrotizing granulomasDiagnostik und TherapieLung transplantationSarcoidosis treatmentSteroid therapyCNS involvementStarting doseSymptomatic therapyOrgan impairmentTherapeutic optionsUnd TherapieEndobronchial ultrasoundSpontaneous resolutionBody weightSarcoidosisOrphan diseaseMonoclonal antibodiesDiseaseSymptomatic patternGranulomas